[HTML][HTML] The pathogenesis of systemic sclerosis: an understanding based on a common pathologic cascade across multiple organs and additional organ-specific …
Y Asano - Journal of clinical medicine, 2020 - mdpi.com
Systemic sclerosis (SSc) is a multisystem autoimmune and vascular disease resulting in
fibrosis of various organs with unknown etiology. Accumulating evidence suggests that a …
fibrosis of various organs with unknown etiology. Accumulating evidence suggests that a …
The pathogenesis of systemic sclerosis
TR Katsumoto, ML Whitfield… - Annual Review of …, 2011 - annualreviews.org
Systemic sclerosis (SSc), also known as scleroderma, is a rare connective tissue disease
characterized by vascular and immune dysfunction, leading to fibrosis that can damage …
characterized by vascular and immune dysfunction, leading to fibrosis that can damage …
Pathophysiology of systemic sclerosis: current understanding and new insights
ABSTRACT Introduction: Systemic sclerosis (SSc) is a complex autoimmune connective
tissue disease characterized by chronic and progressive tissue and organ fibrosis with …
tissue disease characterized by chronic and progressive tissue and organ fibrosis with …
[HTML][HTML] Pathogenesis of systemic sclerosis
D Pattanaik, M Brown, BC Postlethwaite… - Frontiers in …, 2015 - frontiersin.org
Systemic scleroderma (SSc) is one of the most complex systemic autoimmune diseases. It
targets the vasculature, connective tissue-producing cells (namely fibroblasts/myofibroblasts …
targets the vasculature, connective tissue-producing cells (namely fibroblasts/myofibroblasts …
[HTML][HTML] Systemic sclerosis: from pathophysiology to novel therapeutic approaches
D Benfaremo, S Svegliati, C Paolini, S Agarbati… - Biomedicines, 2022 - mdpi.com
Systemic sclerosis (SSc) is a systemic, immune-mediated chronic disorder characterized by
small vessel alterations and progressive fibrosis of the skin and internal organs. The …
small vessel alterations and progressive fibrosis of the skin and internal organs. The …
The pathogenesis of systemic sclerosis revisited
M Geyer, U Müller-Ladner - Clinical reviews in allergy & immunology, 2011 - Springer
Although infectiological stimuli, environmental factors and genotypic features are known to
contribute to the initiation and perpetuation of systemic sclerosis (SSc), its etiology still …
contribute to the initiation and perpetuation of systemic sclerosis (SSc), its etiology still …
Pathogenesis of systemic sclerosis: recent insights of molecular and cellular mechanisms and therapeutic opportunities
J Varga, M Trojanowska… - Journal of Scleroderma …, 2017 - journals.sagepub.com
Systemic sclerosis (SSc) is a complex disease characterized by early microvascular
abnormalities, immune dysregulation and chronic inflammation, and subsequent fibrosis of …
abnormalities, immune dysregulation and chronic inflammation, and subsequent fibrosis of …
Systemic sclerosis: current views of its pathogenesis
CT Derk, SA Jimenez - Autoimmunity reviews, 2003 - Elsevier
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by
severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the …
severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the …
Pathophysiology of systemic sclerosis
B Thoreau, B Chaigne, A Renaud, L Mouthon - La Presse Médicale, 2021 - Elsevier
Systemic sclerosis (SSc) is a rare connective tissue disease characterized by vascular
remodeling, fibroblast activation and extra-cellular matrix production in excess and …
remodeling, fibroblast activation and extra-cellular matrix production in excess and …
Current perspectives on the immunopathogenesis of systemic sclerosis
P Fuschiotti - ImmunoTargets and therapy, 2016 - Taylor & Francis
Systemic sclerosis (SSc or scleroderma) is a progressive and highly debilitating
autoimmune disorder characterized by inflammation, vasculopathy, and extensive fibrosis …
autoimmune disorder characterized by inflammation, vasculopathy, and extensive fibrosis …