G-quadruplexes are non-canonical nucleic acid structures formed by guanine-rich DNA or
RNA sequences. In recent decades, an increasing number of evidences have suggested …

The G-quadruplex structure is a non-canonical secondary DNA motif that is built from planar
tetrads of guanine residues stabilized by Hoogsteen-type hydrogen bonding. Bioinformatics …

Accumulating evidence has linked G-quadruplex structures to a number of biological
processes in vivo, including DNA replication, transcription, and genomic maintenance …

A colorimetric and red-emitting fluorescent dual probe for G-quadruplexes was devised with
a conjugated coumarin–benzothiazole scaffold. Its significant and distinct changes in both …

Background Direct detection of G-quadruplexes in human cells has become an important
issue due to the vital role of G-quadruplex related to biological functions. Despite several …

Mounting evidence supports the presence of biologically relevant G‐quadruplexes in single‐
cell organisms, but the existence of endogenous G‐quadruplex structures in mammalian …

In the present study, we developed a multi-functional guanine derivative, 8FG, as a G-
quadruplex stabilizer, a fluorescent probe for the detection of G-quadruplex formation, and a …

G-quadruplex nucleic acids are four-stranded DNA or RNA secondary structures that are
formed in guanine-rich sequences. These structures exhibit extensive structural …

Here we investigate and reveal the effect of bulge position and bulge identity on G-
quadruplexes using label-free spectroscopic techniques. Notably, we report significant …

Guanine-rich nucleic acids can fold into non-canonical DNA secondary structures called G-
quadruplexes. The formation of these structures can interfere with the biology that is crucial …