IMWG consensus on maintenance therapy in multiple myeloma

H Ludwig, BGM Durie, P McCarthy… - Blood, The Journal …, 2012 - ashpublications.org
Maintaining results of successful induction therapy is an important goal in multiple myeloma.
Here, members of the International Myeloma Working Group review the relevant data …

[HTML][HTML] Posttransplant maintenance therapy in multiple myeloma: the changing landscape

S Sengsayadeth, F Malard, BN Savani, L Garderet… - Blood cancer …, 2017 - nature.com
Transplant-eligible patients with multiple myeloma (MM) now have extended survival after
diagnosis owing to effective modern treatment strategies that include new agents in …

Maintenance therapy with bortezomib plus thalidomide or bortezomib plus prednisone in elderly multiple myeloma patients included in the GEM2005MAS65 trial

MV Mateos, A Oriol, J Martínez-López… - Blood, The Journal …, 2012 - ashpublications.org
Maintenance therapy has become a hot field in myeloma, and it may be particularly relevant
in elderly patients because the major benefit results from the initial therapy. We report the …

[HTML][HTML] European Myeloma Network recommendations on the evaluation and treatment of newly diagnosed patients with multiple myeloma

M Engelhardt, E Terpos, M Kleber, F Gay, R Wäsch… - …, 2014 - ncbi.nlm.nih.gov
Multiple myeloma management has undergone profound changes in the past thanks to
advances in our understanding of the disease biology and improvements in treatment and …

Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial

PG Richardson, P Sonneveld… - Blood, The Journal …, 2007 - ashpublications.org
Initial analysis of the Assessment of Proteasome Inhibition for Extending Remissions (APEX)
trial of relapsed multiple myeloma patients showed significantly longer time to progression …

The role of maintenance thalidomide therapy in multiple myeloma: MRC Myeloma IX results and meta-analysis

GJ Morgan, WM Gregory, FE Davies… - Blood, The Journal …, 2012 - ashpublications.org
Thalidomide maintenance has the potential to modulate residual multiple myeloma (MM)
after an initial response. This trial compared the effect of thalidomide maintenance and no …

Bortezomib and thalidomide maintenance after stem cell transplantation for multiple myeloma: a PETHEMA/GEM trial

L Rosiñol, A Oriol, AI Teruel, AL De La Guía… - Leukemia, 2017 - nature.com
The phase III trial GEM05MENOS65 randomized 390 patients 65 years old or younger with
newly diagnosed symptomatic multiple myeloma (MM) to receive induction with thalidomide …

Frontline therapy of multiple myeloma

P Moreau, M Attal, T Facon - … Journal of the American Society of …, 2015 - ashpublications.org
In the past decade, one of the major advances in the management of patients with
symptomatic newly diagnosed multiple myeloma has been the introduction of novel agents …

Maintenance treatment and survival in patients with myeloma: a systematic review and network meta-analysis

F Gay, G Jackson, L Rosiñol, SA Holstein… - JAMA …, 2018 - jamanetwork.com
Importance Several trials demonstrated the impact of novel agent-based maintenance in
newly diagnosed multiple myeloma (NDMM), but there is no current evidence demonstrating …

Treatment of newly diagnosed myeloma

A Palumbo, SV Rajkumar - Leukemia, 2009 - nature.com
The introduction of thalidomide, bortezomib and lenalidomide has dramatically changed the
treatment paradigm of multiple myeloma (MM). In patients eligible for autologous stem cell …