Abstract Toll-like receptor (TLR) 2 has recently been associated with cellular responses to
numerous microbial products, including LPS and bacterial lipoproteins. However, many …

Two members of the mammalian Toll-like receptor (TLR) family, TLR2 and TLR4, have been
implicated as receptors mediating cellular activation in response to bacterial LPS. Through …

Lipopolysaccharide (LPS) is the main inducer of shock and death in Gram-negative sepsis.
Recent evidence suggests that LPS-induced signal transduction begins with CD14 …

Abstract Toll-like receptor 2 (TLR2)-mediated cell activation induced by commercial
preparations of LPS was recently shown to arise from impurities whose identities are not …

Although genetic studies have revealed a critical role for the toll‐like receptor (TLR) 4 in the
biological response to lipopolysaccharide (LPS), the activities of ectopically expressed TLR4 …

The human homologue of Drosophila Toll (hToll), also called Toll-like receptor 4 (TLR4), is a
recently cloned receptor of the IL-1/Toll receptor family. Interestingly, the TLR4 gene has …

The identification of Toll-like receptors has revolutionised our understanding of innate
immunity. TLR4 transduces the LPS signal and that of a number of structurally and …

Toll-like receptors (TLRs) mediate detection of a broad range of pathogens and pathogen-
derived products including LPS, peptidoglycan, bacterial lipopeptides, and lipoteichoic acid …

Abstract Toll-like receptor (TLR) 2 and TLR4 have been implicated in the responses of cells
to LPS (endotoxin). CD14-transfected Chinese hamster ovary (CHO)-K1 fibroblasts …

We investigated counteracting interactions between the lipopolysaccharides (LPS) from
Escherichia coli (Ec-LPS) and Porphyromonas gingivalis (Pg-LPS), which induce cellular …