Genome editing has been a transformative force in the life sciences and human medicine,
offering unprecedented opportunities to dissect complex biological processes and treat the …

CRISPR-based genome editing holds promise for genome engineering and other
applications in diverse organisms. Defining and improving the genome-wide and …

Our ability to edit genomes lags behind our capacity to sequence them, but the growing
understanding of CRISPR biology and its application to genome, epigenome and …

The development of CRISPR-derived genome editing technologies has enabled the precise
manipulation of DNA sequences within the human genome. In this review, we discuss the …

Genome editing took a dramatic turn with the development of the clustered regularly
interspaced short palindromic repeats (CRISPR)-CRISPR-associated proteins (Cas) system …

Precise nucleic acid editing technologies have facilitated the research of cellular function
and the development of novel therapeutics, especially the current programmable nucleases …

The recent development of the CRISPR/Cas9 system as an efficient and accessible
programmable genome‐editing tool has revolutionized basic science research …

The CRISPR-Cas genome editing tools have been adopted rapidly in the research
community, and they are quickly finding applications in the commercial sector as well. Lest …

Advances in sequencing technologies have facilitated the discovery of previously unknown
genetic variants in both inherited and acquired disorders, and tools to correct these …

The CRISPR-Cas system offers a programmable platform for eukaryotic genome and
epigenome editing. The ability to perform targeted genetic and epigenetic perturbations …