Matrix metalloproteinases (MMPs) are the most prominent proteinases involved in
tumorigenesis. They were initially recognized to promote tumor progression by remodeling …

Members of the matrix metalloproteinase (MMP) family have been identified as poor
prognosis markers for breast cancer patients and as drivers of many facets of the tumor …

The restricted view of matrix metalloproteinases (MMPs) as simple destroyers of
extracellular matrix components has largely ignored their substantial contribution in many …

Matrix metalloproteinases (MMPs) are a family of zinc endopeptidases that cleave nearly all
components of the extracellular matrix as well as many other soluble and cell‐associated …

Matrix metalloproteinases (MMPs) are members of zinc-dependent endopeptidases
implicated in a variety of physiological and pathological processes. Over the decades …

Traditionally, matrix metalloproteinases (MMPs) have been implicated in cancer invasion
and metastasis. Because of their role in these processes, several MMPs have been …

A major hallmark of malignant disease is the capacity of cancer cells to cross tissue
boundaries and spread to distant sites throughout the body. Extracellular matrix-degrading …

Abstract Background Matrix metalloproteinases (MMPs) are a family of structural and
functional related endopeptidases. They play a crucial role in tumor invasion and building of …

The first matrix metalloproteinase (MMP) was discovered in 1962 from the tail of a tadpole by
its ability to degrade collagen. As their name suggests, matrix metalloproteinases are …

Matrix metalloproteinases (MMPs) are a family of extracellular matrix degrading proteinases.
Owing to their matrix-degrading abilities and high expression in advanced tumors, MMPs …