The aryl hydrocarbon receptor (Ahr) is a ligand-dependent transcription factor and facilitates
immune cell environmental sensing through its activation by cellular, dietary, and microbial …

With striking similarity to their adaptive T helper cell counterparts, innate lymphoid cells
(ILCs) represent an emerging family of cell types that express signature transcription factors …

The adaptive immune system, composed of lymphocytes, recognizes diversified antigens
and generates immunological memory. According to the canonical model, it is the innate …

The aryl hydrocarbon receptor (AHR) is an important regulator of the development and
function of both innate and adaptive immune cells through roles associated with AHR's …

The ligand-activated aryl hydrocarbon receptor (AHR) is known to modulate many genes in
a highly cell-specific manner, either directly or indirectly via secondary effects. In contrast …

As a ligand-activated transcription factor, the aryl hydrocarbon receptor (AhR) is activated by
structurally diverse ligands derived from the environment, diet, microorganisms, and …

Innate lymphoid cells (ILCs) expressing the nuclear receptor RORγt are essential for gut
immunity presumably through production of interleukin-22 (IL-22). The molecular …

The aryl hydrocarbon receptor (AhR) is a versatile environmental sensor and transcription
factor found throughout the body, responding to a wide range of small molecules originating …

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is
activated by small molecules provided by the diet, microorganisms, metabolism, and …

The intestinal immune system is challenged daily with the task of recognizing and
eliminating pathogens while simultaneously tolerating dietary and commensal antigens. All …