[HTML][HTML] Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their …

FN Varra, M Varras, VK Varra… - Molecular …, 2024 - spandidos-publications.com
Obesity reaches up to epidemic proportions globally and increases the risk for a wide
spectrum of co-morbidities, including type-2 diabetes mellitus (T2DM), hypertension …

[HTML][HTML] The Interplay between Obesity and Inflammation

I Savulescu-Fiedler, R Mihalcea, S Dragosloveanu… - Life, 2024 - mdpi.com
Obesity is an important condition affecting the quality of life of numerous patients and
increasing their associated risk for multiple diseases, including tumors and immune …

[HTML][HTML] Chronic adipose tissue inflammation linking obesity to insulin resistance and type 2 diabetes

F Zatterale, M Longo, J Naderi, GA Raciti… - Frontiers in …, 2020 - frontiersin.org
Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …

The evolving role of inflammation in obesity and the metabolic syndrome

YH Lee, RE Pratley - Current diabetes reports, 2005 - Springer
Advances in adipose tissue biology over the past 10 years have led to an improved
understanding of the mechanisms linking obesity with the metabolic syndrome and other …

Inflammation, obesity and rheumatic disease: common mechanistic links. A narrative review

E Nikiphorou, GE Fragoulis - Therapeutic Advances in …, 2018 - journals.sagepub.com
Obesity represents a rising global health concern, linked to significant social, psychological
and physical burden to the individual affected, people around them and the society as a …

The evil axis of obesity, inflammation and type-2 diabetes

A Das, S Mukhopadhyay - Endocrine, Metabolic & Immune …, 2011 - ingentaconnect.com
Obesity and type 2 diabetes (T2D) are global problems affecting all age groups and have
been characterized as lifestyle disorders. Though no study has clearly proved a direct …

The key role of inflammation in the pathogenesis and management of obesity and CVD

C Boutari, MA Hill, C Procaccini, G Matarese… - Metabolism, 2023 - Elsevier
Metabolic syndrome (MetS) includes a variety of cardiovascular risk factors, such as visceral
obesity, hypertension, dyslipidemia and insulin resistance, which are associated with the …

Metabolic syndrome, insulin resistance, and roles of inflammation–mechanisms and therapeutic targets

GR Romeo, J Lee, SE Shoelson - Arteriosclerosis, thrombosis, and …, 2012 - Am Heart Assoc
Obesity and its comorbidities, including type 2 diabetes mellitus and cardiovascular disease,
are associated with a state of chronic low-grade inflammation that can be detected both …

Recent insights on modulation of inflammasomes by adipokines: a critical event for the pathogenesis of obesity and metabolism-associated diseases

DV Pham, PH Park - Archives of pharmacal research, 2020 - Springer
Aberrant production of adipokines, a group of adipocytes-derived hormones, is considered
one of the most important pathological characteristics of obesity. In individuals with obesity …

Mechanisms of chronic state of inflammation as mediators that link obese adipose tissue and metabolic syndrome

E Fuentes, F Fuentes, G Vilahur… - Mediators of …, 2013 - Wiley Online Library
The metabolic syndrome is a cluster of cardiometabolic alterations that include the presence
of arterial hypertension, insulin resistance, dyslipidemia, and abdominal obesity. Obesity is …