Longitudinal observations on mutations conferring ganciclovir resistance in patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis: The …

DA Jabs, BK Martin, MS Forman, JP Dunn… - American journal of …, 2001 - Elsevier
PURPOSE: Cytomegalovirus retinitis is the most common intraocular infection in patients
with acquired immunodeficiency syndrome (AIDS). With prolonged suppressive …

Mutations conferring ganciclovir resistance in a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis

DA Jabs, BK Martin, MS Forman… - The Journal of …, 2001 - academic.oup.com
Cytomegalovirus (CMV) retinitis is among the most common opportunistic infections in
patients with acquired immunodeficiency syndrome. In a prospective study of 210 patients …

Emergence of drug-resistant cytomegalovirus retinitis in the contralateral eyes of patients with AIDS treated with ganciclovir

Y Imai, C Shum, DF Martin… - The Journal of …, 2004 - academic.oup.com
The purpose of the present study was to examine the emergence of ganciclovir-resistant
virus in the contralateral eyes of patients who received treatment for cytomegalovirus retinitis …

Change over time in incidence of ganciclovir resistance in patients with cytomegalovirus retinitis

BK Martin, MO Ricks, MS Forman… - Clinical infectious …, 2007 - academic.oup.com
Background. In the mid-1990s, the incidence of cytomegalovirus (CMV) resistance to
ganciclovir was estimated to be∼ 25% by 1 year after diagnosis of retinitis in patients with …

Cytomegalovirus resistance to ganciclovir and clinical outcomes of patients with cytomegalovirus retinitis

DA Jabs, BK Martin, MS Forman, L Hubbard… - American journal of …, 2003 - Elsevier
PURPOSE: To evaluate whether cytomegalovirus resistant to ganciclovir, detected in either
the blood or urine, correlates with adverse ocular outcomes. DESIGN: Prospective cohort …

Viral sensitivity testing in patients with cytomegalovirus retinitis clinically resistant to foscarnet or ganciclovir

JP Dunn, MW MacCUMBER, MS Forman… - American journal of …, 1995 - Elsevier
Purpose Resistance to antiviral therapy is a potential cause of progression of
cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. We …

Detection of ganciclovir resistance in patients with AIDS and cytomegalovirus retinitis: correlation of genotypic methods with viral phenotype and clinical outcome

DA Jabs, BK Martin, MO Ricks… - Journal of Infectious …, 2006 - academic.oup.com
Abstract Background The cytomegalovirus (CMV) UL97 gene can be sequenced either from
blood specimens directly amplified by polymerase chain reaction (PCR) or from culture …

Cytomegalovirus retinitis and viral resistance: ganciclovir resistance

DA Jabs, C Enger, JP Dunn, M Forman… - The Journal of …, 1998 - academic.oup.com
Cytomegalovirus (CMV) retinitis is among the most common opportunistic infections in
patients with AIDS and a substantial cause of visual loss. With long-term therapy, resistant …

Cytomegalovirus (CMV) resistance in patients with CMV retinitis and AIDS treated with oral or intravenous ganciclovir

WL Drew, MJ Stempien, J Andrews… - The Journal of …, 1999 - academic.oup.com
Abstract Treatment of cytomegalovirus (CMV) retinitis with oral ganciclovir results in
relatively low plasma concentrations of drug, which theoretically could cause more frequent …

Cytomegalovirus retinitis and viral resistance: prevalence of resistance at diagnosis, 1994

DA Jabs, JP Dunn, C Enger, M Forman… - Archives of …, 1996 - jamanetwork.com
Objective: To determine the prevalence of cytomegalovirus (CMV) isolates resistant to
ganciclovir sodium or foscarnet sodium at the time of diagnosis of CMV retinitis, prior to the …