Streptococcus mitis: walking the line between commensalism and pathogenesis

J Mitchell - Molecular oral microbiology, 2011 - Wiley Online Library
Streptococcus mitis is a viridans streptococcus and a normal commensal of the human
oropharynx. However, S. mitis can escape from this niche and cause a variety of infectious …

The pathogenic persona of community‐associated oral streptococci

SE Whitmore, RJ Lamont - Molecular microbiology, 2011 - Wiley Online Library
The mitis group streptococci (MGS) are widespread in the oral cavity and are traditionally
associated with oral health. However, these organisms have many attributes that contribute …

The Biology of Streptococcus mutans

JA Lemos, SR Palmer, L Zeng, ZT Wen… - Microbiology …, 2019 - Am Soc Microbiol
As a major etiological agent of human dental caries, Streptococcus mutans resides primarily
in biofilms that form on the tooth surfaces, also known as dental plaque. In addition to caries …

StreptoBase: An Oral Streptococcus mitis Group Genomic Resource and Analysis Platform

W Zheng, TK Tan, IC Paterson, NVR Mutha, CC Siow… - PloS one, 2016 - journals.plos.org
The oral streptococci are spherical Gram-positive bacteria categorized under the phylum
Firmicutes which are among the most common causative agents of bacterial infective …

The Genome of Streptococcus mitis B6 - What Is a Commensal?

D Denapaite, R Brückner, M Nuhn, P Reichmann… - PloS one, 2010 - journals.plos.org
Streptococcus mitis is the closest relative of the major human pathogen S. pneumoniae. The
2, 15 Mb sequence of the Streptococcus mitis B6 chromosome, an unusually high-level beta …

Innocent until proven guilty: mechanisms and roles of Streptococcus–Candida interactions in oral health and disease

H Xu, HF Jenkinson… - Molecular oral …, 2014 - Wiley Online Library
Candida albicans and streptococci of the mitis group colonize the oral cavities of the majority
of healthy humans. While C. albicans is considered an opportunistic pathogen, streptococci …

How to become a killer, or is it all accidental? Virulence strategies in oral streptococci

I Sitkiewicz - Molecular oral microbiology, 2018 - Wiley Online Library
Streptococci are a diverse group of Gram‐positive microorganisms sharing common
virulence traits and similar strategies to escape the oral niche and establish an infection in …

Genomic and phenotypic diversity of Streptococcus mutans

CM Bedoya-Correa, RJR Rodríguez… - Journal of Oral …, 2019 - Elsevier
Background Streptococcus mutans (S. mutans) is a commensal microorganism found in the
human oral cavity. However, due to environmental changes, selective pressures, and the …

The road less traveled – defining molecular commensalism with Streptococcus sanguinis

J Kreth, RA Giacaman, R Raghavan… - Molecular Oral …, 2017 - Wiley Online Library
The commensal oral microbial flora has evolved with the human host to support colonization
of the various intraoral sites without triggering a significant immune response. In exchange …

Lessons learned from clinical studies: roles of mutans streptococci in the pathogenesis of dental caries

RO Mattos-Graner, MI Klein, DJ Smith - Current Oral Health Reports, 2014 - Springer
Dental caries is a major health problem worldwide. This disease results from improper
interactions between oral microorganisms and host that stimulate the establishment of …