To persist in the oral cavity, bacteria must be able to tolerate rapid and substantial
environmental fluctuations, particularly in pH and nutrient source and availability. Various …

Resistance to phagocytosis is a hallmark of virulent Streptococcus pyogenes (group A
streptococcus). Surface-bound C5a peptidase reduces recruitment of phagocytes to the site …

The complete genome sequence of Streptococcus mutans, a bacterial pathogen commonly
associated with human dental caries, was published in 2002. The streamlined genome (2.03 …

Group A Streptococcus is a leading human pathogen associated with a diverse array of
mucosal and systemic infections. Cell wall anchored pili were recently described in several …

Streptococcus mutans is widely recognized as one of the key etiological agents of human
dental caries. Despite its role in this important disease, our present knowledge of gene …

Genome sequencing of group A Streptococcus (GAS) has revealed that prophages account
for the vast majority of gene content differences between strains. Serotype M28 strains are a …

Although it is one of the most common ailments on the planet, dental caries, more commonly
known as cavities, remains a poorly understood disease. Caries are caused by a complex …

Many human pathogens produce phenotypic variants as a means to circumvent the host
immune system and enhance survival and, as a potential consequence, exhibit increased …

Streptococcus pyogenes ranks among the main causes of mortality from bacterial infections
worldwide. Currently there is no vaccine to prevent diseases such as rheumatic heart …

Analysis of multiple group A Streptococcus (GAS) genomes shows that genes encoding
proteins involved in carbohydrate utilization comprise some 15% of the core GAS genome …