Streptococci readily colonize mucosal tissues in the nasopharynx; the respiratory,
gastrointestinal, and genitourinary tracts; and the skin. Each ecological niche presents a …

The global distribution of individual species of oral bacteria demonstrates their ability to
survive among their human hosts. Such an ubiquitous existence is the result of efficient …

The oral microbial flora comprises one of the most diverse human-associated biofilms. Its
development is heavily influenced by oral streptococci, which are considered the main …

ABSTRACT Although Streptococcus intermedius and Streptococcus mutans are regarded as
members of the commensal microflora of the body, S. intermedius is often associated with …

Dental caries is one of the most prevalent diseases in humans, second only to the common
cold. It causes irreversible damage to the grinding machinery involved in the intake of food …

The genetically diverse viridans group streptococci (VGS) are increasingly recognized as
the cause of a variety of human diseases. We used a recently developed multilocus …

Group A Streptococcus (GAS) causes an exceptionally broad range of infections in humans,
from relatively mild pharyngitis and skin infections to life-threatening necrotizing fasciitis and …

Streptococcus pyogenes causes 700 million human infections annually worldwide, yet,
despite a century of intensive effort, there is no licensed vaccine against this bacterium …

The M protein of group A streptococcus (GAS) is considered to be a major virulence factor
because it renders GAS resistant to phagocytosis and allows bacterial growth in human …

Introduction 2.1. Group A streptococci 2.2. Streptococcal diseases 2.3. Genomic sequencing
3. Virulence Factors 3.1. Cell–associated factors 3.1. 1. M-protein superfamily 3.1. 1.1. M …