The importance of fluorine in the life science industry

P Maienfisch, RG Hall - Chimia, 2004 - chimia.ch
Fluorine-containing compounds are at the leading edge of many new developments in the
life science industry. In recent years a steady increase in the number of fluorinated organic …

Successful fluorine-containing herbicide agrochemicals

T Fujiwara, D O'Hagan - Journal of Fluorine Chemistry, 2014 - Elsevier
Of the herbicides licensed worldwide, currently around 25% contain at least one fluorine
atom and many contain multiple fluorines in the form of difluoro-and trifluoromethyl groups …

Recent developments in fluorine‐containing pesticides

P Jeschke - Pest Management Science, 2024 - Wiley Online Library
To ensure ongoing sustainability, the modern agrochemical industry is faced with enormous
challenges. These arise from provision of high‐quality food to increasing water use and …

Fluorine in health care: Organofluorine containing blockbuster drugs

D O'Hagan - Journal of Fluorine Chemistry, 2010 - Elsevier
Organic fluorine compounds have had a profound impact on the development of bioactives
for the modern pharmaceuticals market. It is estimated that up to 20% of pharmaceuticals …

[图书][B] Fluorine in medicinal chemistry and chemical biology

I Ojima - 2009 - books.google.com
The extraordinary potential of fluorine-containing molecules in medicinal chemistry and
chemical biology has been recognized by researchers outside of the traditional fluorine …

Next generation of fluorine-containing pharmaceuticals, compounds currently in phase II–III clinical trials of major pharmaceutical companies: new structural trends …

Y Zhou, J Wang, Z Gu, S Wang, W Zhu… - Chemical …, 2016 - ACS Publications
Fluoroorganic chemistry has become essential in the evolution of many different but
interconnected research fields. These include the development of new materials with a …

Application of fluorine in drug design during 2010-2015 years: a mini-review

BC Wang, LJ Wang, B Jiang, SY Wang… - Mini reviews in …, 2017 - ingentaconnect.com
Background: The widespread application of fluorine in drug design benefits from distinctive
properties. Incorporation of fluorine can positively modulate certain pharmacokinetics …

Future challenges and opportunities with fluorine in drugs?

D O'Hagan, RJ Young - Medicinal Chemistry Research, 2023 - Springer
Contributed comment to the special Issue of Medicinal Chemistry Research marking the
retirement of Dr Nicholas Meanwell from Bristol Myers Squibb. The increasing incorporation …

The many roles for fluorine in medicinal chemistry

WK Hagmann - Journal of medicinal chemistry, 2008 - ACS Publications
Drug candidates with one or more fluorines have become commonplace. The special nature
of fluorine imparts a variety of properties to certain medicines, including enhanced binding …

[图书][B] Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics, and Agrochemicals: Progress in Fluorine Science Series

G Haufe, F Leroux - 2018 - books.google.com
Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics and Agrochemicals,
volume four in Alain Tressaud's Progress in Fluorine Science series, presents a critical …