[HTML][HTML] Influence of renal function on the pharmacokinetics, pharmacodynamics, efficacy, and safety of non–vitamin K antagonist oral anticoagulants

MR Weir, R Kreutz - Mayo Clinic Proceedings, 2018 - Elsevier
With the growing integration of non–vitamin K antagonist oral anticoagulants (NOACs) into
clinical practice, questions have arisen regarding their use in special populations, including …

Comparative effectiveness and safety of non–vitamin K antagonist oral anticoagulants in atrial fibrillation patients

W Zhu, Z Ye, S Chen, D Wu, J He, Y Dong, GYH Lip… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Several observational studies have compared the effect of the
non–vitamin K antagonist oral anticoagulants to each other in patients with atrial fibrillation …

Non-vitamin K antagonist oral anticoagulants: impact of non-adherence and discontinuation

JM Rivera-Caravaca, MA Esteve-Pastor… - Expert Opinion on …, 2017 - Taylor & Francis
ABSTRACT Introduction: Non-Vitamin K Antagonist Oral Anticoagulants (NOACs) are at
least as effective as vitamin K antagonists (VKAs) reducing thromboembolism and mortality …

[HTML][HTML] Effectiveness and safety of non-vitamin K oral anticoagulants in non-valvular atrial fibrillation patients: Results of A real-world study in a metropolitan area of …

E Crocetti, S Cattaneo, W Bergamaschi… - Journal of Clinical …, 2021 - mdpi.com
Background: New oral anticoagulant agents (NOACs) are valid alternatives for vitamin K
antagonists (VKA) in patients with non-valvular atrial fibrillation (NVAF) for stroke prevention …

Novel oral anticoagulants for the prevention of stroke in patients with atrial fibrillation and hypertension: a meta-analysis

Y Zheng, Y Liu, J Bi, W Lai, C Lin, J Zhu, W Yao… - American Journal of …, 2019 - Springer
Introduction Hypertension is associated with increased risk of stroke and bleeding in
patients with atrial fibrillation (AF). In the present study, we aimed to investigate the influence …

Fitting the right non-vitamin K antagonist oral anticoagulant to the right patient with non-valvular atrial fibrillation: an evidence-based choice

YG Li, D Pastori, GYH Lip - Annals of Medicine, 2018 - Taylor & Francis
Atrial fibrillation (AF) is the most prevalent arrhythmia and is associated with an increased
risk of ischemic stroke (IS) and systemic embolism (SE). Stroke prevention is a key element …

Non-vitamin K antagonist oral anticoagulants for stroke prevention in atrial fibrillation: safety issues in the elderly

T Ajam, TL Cumpian, BL Tilkens… - Expert Review of …, 2020 - Taylor & Francis
Introduction Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly used for
stroke prevention in patients with atrial fibrillation (AF). Since NOACs are predominantly …

[HTML][HTML] Consistency of safety and efficacy of new oral anticoagulants across subgroups of patients with atrial fibrillation

JC Lega, L Bertoletti, C Gremillet, C Chapelle… - PloS one, 2014 - journals.plos.org
Aims The well-known limitations of vitamin K antagonists (VKA) led to development of new
oral anticoagulants (NOAC) in non-valvular atrial fibrillation (NVAF). The aim of this meta …

Efficacy and Safety of Non–Vitamin-K Antagonist Oral Anticoagulants Versus Warfarin Across the Spectrum of Body Mass Index and Body Weight: An Individual …

SM Patel, E Braunwald, J Steffel, G Boriani… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The efficacy and safety of non–vitamin-K antagonist oral anticoagulants
(NOACs) across the spectrum of body mass index (BMI) and body weight (BW) remain …

[HTML][HTML] Risk of fatal bleeding in episodes of major bleeding with new oral anticoagulants and vitamin K antagonists: a systematic review and meta-analysis

J Skaistis, T Tagami - PloS one, 2015 - journals.plos.org
Background The reversibility of new/novel oral anticoagulants (NOAC) is not well
understood, whereas the reversal strategies for bleeding associated with vitamin k …