Phospholipid scramblase 1.

Y Huang, Q Zhao, GQ Chen - Sheng li xue bao:[Acta Physiologica …, 2006 - europepmc.org
Phospholipid scramblase 1 (PLSCR1) is a calcium-binding, multiply palmitoylated type II
endofacial plasma membrane protein, while unpalmitoylated PLSCR1 protein can import …

Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells

Y Huang, Q Zhao, CX Zhou, ZM Gu, D Li, HZ Xu… - Oncogene, 2006 - nature.com
Abstract Phospholipid scramblase 1 (PLSCR1) is a multiply palmitoylated protein which is
localized in either the cell membrane or nucleus depending on its palmitoylated state. The …

Two c-Myc binding sites are crucial in upregulating the expression of human phospholipid scramblase 1 gene

JM Vinnakota, SN Gummadi - Biochemical and biophysical research …, 2016 - Elsevier
Abstract Human phospholipid scramblase 1 (hPLSCR1) is a type II endofacial membrane
protein which mediates bi-directional transport of phospholipids across the plasma …

[HTML][HTML] Identification and characterization of the novel nuclease activity of human phospholipid scramblase 1

U Sivagnanam, S Narayana Murthy, SN Gummadi - BMC biochemistry, 2016 - Springer
Background Human phospholipid scramblase 1 (hPLSCR1) was initially identified as a Ca
2+ dependent phospholipid translocator involved in disrupting membrane asymmetry …

Phospholipid scramblase 1 acts through the IL-6/JAK/STAT3 pathway to promote the malignant progression of glioma

SZ Zhou, J Xu, YF Zhu - Archives of Biochemistry and Biophysics, 2024 - Elsevier
Abstract Background Phospholipid scramblase 1 (PLSCR1) is a calcium-dependent
endofacial plasma-membrane protein that plays an essential role in multiple human …

[HTML][HTML] Blockade of phospholipid scramblase 1 with its N-terminal domain antibody reduces tumorigenesis of colorectal carcinomas in vitro and in vivo

CW Fan, CY Chen, KT Chen, CR Shen, YB Kuo… - Journal of translational …, 2012 - Springer
Background Membrane-bound phospholipid scramblase 1 (PLSCR1) is involved in both
lipid trafficking and cell signaling. Previously, we showed that PLSCR1 is overexpressed in …

[HTML][HTML] RNA interference‑mediated downregulation of phospholipid scramblase 1 expression in primary liver cancer in vitro

L Gui, YW Zhu, Q Xu, JJ Huang, P Hua… - Oncology …, 2020 - spandidos-publications.com
Abstract Phospholipid scramblase 1 (PLSCR1) serves a function in the pathogenesis and
progression of various types of cancer. However, the role of PLSCR1 in human primary liver …

[HTML][HTML] Phospholipid scramblase 1: a protein with multiple functions via multiple molecular interactors

J Dal Col, MJ Lamberti, A Nigro, V Casolaro… - Cell Communication and …, 2022 - Springer
Abstract Phospholipid scramblase 1 (PLSCR1) is the most studied protein of the scramblase
family. Originally, it was identified as a membrane protein involved in maintaining plasma …

Palmitoylation of phospholipid scramblase 1 controls its distribution between nucleus and plasma membrane

T Wiedmer, J Zhao, M Nanjundan, PJ Sims - Biochemistry, 2003 - ACS Publications
Phospholipid scramblase 1 (PLSCR1) is a Ca2+-binding, endofacial plasma membrane
protein thought to contribute to the transbilayer movement of phosphatidylserine and other …

Phospholipid Scramblase 1 Is Imported into the Nucleus by a Receptor-Mediated Pathway and Interacts with DNA,

I Ben-Efraim, Q Zhou, T Wiedmer, L Gerace… - Biochemistry, 2004 - ACS Publications
Phospholipid scramblase 1 (PLSCR1) is a multiply palmitoylated, Ca2+-binding, endofacial
plasma membrane protein originally identified by its capacity to accelerate transbilayer …