Managing the safety of inhaled corticosteroids in COPD and the risk of pneumonia

A Liapikou, M Toumbis, A Torres - Expert Opinion on Drug Safety, 2015 - Taylor & Francis
Introduction: Inhaled corticosteroids (ICS) are known to increase the risk of pneumonia in
patients with chronic obstructive pulmonary disease. To estimate the association between …

[HTML][HTML] Inhaled corticosteroids and the pneumonia risk in patients with chronic obstructive pulmonary disease: a meta-analysis of randomized controlled trials

H Chen, J Sun, Q Huang, Y Liu, M Yuan… - Frontiers in …, 2021 - frontiersin.org
Background: Whether all types of inhaled corticosteroids (ICSs) would increase the
pneumonia risk in patients with chronic obstructive pulmonary disease (COPD) remains …

[HTML][HTML] Risk of pneumonia with inhaled corticosteroid versus long-acting bronchodilator regimens in chronic obstructive pulmonary disease: a new-user cohort study

RL DiSantostefano, T Sampson, HV Le, D Hinds… - PLoS …, 2014 - journals.plos.org
Introduction Observational studies using case-control designs have showed an increased
risk of pneumonia associated with inhaled corticosteroid (ICS)-containing medications in …

Inhaled corticosteroids and risk of pneumonia in patients with chronic obstructive pulmonary disease: a meta-analysis of randomized controlled trials

M Yang, Y Du, H Chen, D Jiang, Z Xu - International immunopharmacology, 2019 - Elsevier
Objective Inhaled corticosteroids (ICS) are generally used to treat patients with chronic
obstructive pulmonary disease (COPD) who suffer from repeated exacerbations. Recently, it …

Inhaled corticosteroids and the increased risk of pneumonia: what's new? A 2015 updated review

H Iannella, C Luna, G Waterer - Therapeutic advances in …, 2016 - journals.sagepub.com
There is a considerable amount of evidence that supports the possibility of an increased risk
of pneumonia associated with prolonged use of inhaled corticosteroids (ICS) in patients with …

Inhaled corticosteroids in chronic obstructive pulmonary disease: how significant is the risk of pneumonia and should it impact use of inhaled corticosteroids?

R Cavallazzi, S Singh - Current infectious disease reports, 2011 - Springer
Patients with chronic obstructive pulmonary disease (COPD) are at an increased risk of
infections such as pneumonia. Pneumonia among patients with COPD carries a higher risk …

[HTML][HTML] Concomitant inhaled corticosteroid use and the risk of pneumonia in COPD: a matched-subgroup post hoc analysis of the UPLIFT® trial

DP Tashkin, M Miravitlles, BR Celli, N Metzdorf… - Respiratory …, 2018 - Springer
Background Use of inhaled corticosteroids (ICS) increases the risk of pneumonia in chronic
obstructive pulmonary disease (COPD), but the magnitude of risk with different ICS remains …

Association of inhaled corticosteroids with incident pneumonia and mortality in COPD patients; systematic review and meta-analysis

E Festic, V Bansal, E Gupta… - COPD: Journal of Chronic …, 2016 - Taylor & Francis
Background: Inhaled corticosteroids are commonly prescribed for patients with severe
COPD. They have been associated with increased risk of pneumonia but not with increased …

The dose of inhaled corticosteroids in patients with COPD: when less is better

JL Izquierdo, BG Cosio - International Journal of Chronic …, 2018 - Taylor & Francis
Background The use of inhaled corticosteroids (ICS) in combination with bronchodilators in
patients with COPD has been shown to decrease the rate of disease exacerbations and to …

Discontinuation of inhaled corticosteroids in COPD and the risk reduction of pneumonia

S Suissa, J Coulombe, P Ernst - Chest, 2015 - Elsevier
Background The widespread use of inhaled corticosteroids (ICSs) for COPD treatment has
been questioned. Recent studies of weaning some patients with COPD off ICSs found little …