Biomaterials-mediated engineering of the immune system
C Backlund, S Jalili-Firoozinezhad… - Annual review of …, 2023 - annualreviews.org
Modulation of the immune system is an important therapeutic strategy in a wide range of
diseases, and is fundamental to the development of vaccines. However, optimally safe and …
diseases, and is fundamental to the development of vaccines. However, optimally safe and …
Engineering vaccines and niches for immune modulation
Controlled modulation of immune response, especially the balance between
immunostimulatory and immunosuppressive responses, is critical for a variety of clinical …
immunostimulatory and immunosuppressive responses, is critical for a variety of clinical …
Biomaterial strategies for immunomodulation
Strategies to enhance, suppress, or qualitatively shape the immune response are of
importance for diverse biomedical applications, such as the development of new vaccines …
importance for diverse biomedical applications, such as the development of new vaccines …
Targeted modulation of immune cells and tissues using engineered biomaterials
P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
Engineering biomaterials to direct innate immunity
Small alterations during early stages of innate immune response can drive large changes in
how adaptive immune cells develop and function during protective immunity or disease …
how adaptive immune cells develop and function during protective immunity or disease …
Immunological principles regulating immunomodulation with biomaterials
The immune system has evolved to recognize and eliminate pathogens; this recognition
relies on the identification of structural molecular patterns within unique tissue …
relies on the identification of structural molecular patterns within unique tissue …
Leveraging the modularity of biomaterial carriers to tune immune responses
SJ Tsai, SK Black, CM Jewell - Advanced functional materials, 2020 - Wiley Online Library
Biomaterial carriers offer modular features to control the delivery and presentation of
vaccines and immunotherapies. This tunability is a distinct capability of biomaterials …
vaccines and immunotherapies. This tunability is a distinct capability of biomaterials …
Designing biomaterials with immunomodulatory properties for tissue engineering and regenerative medicine
JI Andorko, CM Jewell - Bioengineering & translational …, 2017 - Wiley Online Library
Recent research in the vaccine and immunotherapy fields has revealed that biomaterials
have the ability to activate immune pathways, even in the absence of other immune …
have the ability to activate immune pathways, even in the absence of other immune …
Material matters: exploring the interplay between natural biomaterials and host immune system
AS Tripathi, MEA Zaki, SA Al-Hussain… - Frontiers in …, 2023 - frontiersin.org
Biomaterials are widely used for various medical purposes, for instance, implants, tissue
engineering, medical devices, and drug delivery systems. Natural biomaterials can be …
engineering, medical devices, and drug delivery systems. Natural biomaterials can be …
Immunologically effective biomaterials
Q Wei, Y Su, H Xin, L Zhang, J Ding… - ACS Applied Materials & …, 2021 - ACS Publications
Immunoregulation represents a booming field of biomaterial design. The unique physical
and chemical properties of biomaterials offer tremendous opportunities for development …
and chemical properties of biomaterials offer tremendous opportunities for development …