Molecular pathogenesis and targeted therapy of sporadic pancreatic neuroendocrine tumors

G Capurso, L Archibugi… - Journal of Hepato‐Biliary …, 2015 - Wiley Online Library
Over the past few years, knowledge regarding the molecular pathology of sporadic
pancreatic neuroendocrine tumors (PNETs) has increased substantially, and a number of …

Molecular profiling of pancreatic neuroendocrine tumors (pNETS) and the clinical potential

M Camilli, K Papadimitriou, A Nogueira… - Expert review of …, 2018 - Taylor & Francis
Introduction: Pancreatic neuroendocrine tumors (pNETs) represent a small part of pancreatic
neoplasms, and the knowledge about their indolent clinical course remains a subject of …

Molecular pathogenesis of pancreatic neuroendocrine tumors

F Ehehalt, E Franke, C Pilarsky, R Grützmann - Cancers, 2010 - mdpi.com
Pancreatic neuroendocrine tumors (PNETs) are rare primary neoplasms of the pancreas
and arise sporadically or in the context of genetically determined syndromes. Depending on …

Pancreatic neuroendocrine tumors: molecular mechanisms and therapeutic targets

CK Maharjan, PH Ear, CG Tran, JR Howe… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic neuroendocrine tumors (pNETs) are rare, indolent cancers
whose causation is only partly understood. An increasing number of studies have uncovered …

Pancreatic neuroendocrine tumors: current opinions on a rare, but potentially curable neoplasm

D Karakaxas, M Gazouli, T Liakakos… - European Journal of …, 2014 - journals.lww.com
Pancreatic neuroendocrine tumors (PNETs) share a unique genetic identity, functional
behavior, and clinical course. Compared with tumors of the exocrine pancreas, they are rare …

Well-differentiated pancreatic neuroendocrine tumors: from genetics to therapy

RF De Wilde, BH Edil, RH Hruban… - Nature Reviews …, 2012 - nature.com
Well-differentiated pancreatic neuroendocrine tumors (PanNETs) comprise∼ 1–3% of
pancreatic neoplasms. Although long considered as reasonably benign lesions, PanNETs …

Molecular profile of pancreatic neuroendocrine neoplasms (PanNENs): Opportunities for personalized therapies

J Arakelyan, D Zohrabyan, PA Philip - Cancer, 2021 - Wiley Online Library
Pancreatic neuroendocrine neoplasms (panNENs) are the second most common epithelial
tumors of the pancreas. Despite improvements in prognostic grading and staging systems, it …

[HTML][HTML] Pancreatic neuroendocrine tumors: biology, diagnosis, and treatment

C Ro, W Chai, EY Victoria, R Yu - Chinese journal of cancer, 2013 - ncbi.nlm.nih.gov
Pancreatic neuroendocrine tumors (PNETs), a group of endocrine tumors arising in the
pancreas, are among the most common neuroendocrine tumors. The genetic causes of …

Molecular biology of pancreatic neuroendocrine tumors: From mechanism to translation

X Shen, X Wang, X Lu, Y Zhao, W Guan - Frontiers in Oncology, 2022 - frontiersin.org
Pancreatic neuroendocrine tumors (pNETs) are a group of heterogeneous tumors originated
from progenitor cells. As these tumors are predominantly non-functional, most of them …

Translational diagnostics and therapeutics in pancreatic neuroendocrine tumors

JE Maxwell, SK Sherman, JR Howe - Clinical cancer research, 2016 - AACR
Pancreatic neuroendocrine tumors (PNET) are rare tumors, but have been increasing in
incidence. Although typically thought of as indolent, more than half of patients present with …