Molecular basis for “null” lipoprotein (a) phenotypes and the influence of apolipoprotein (a) size on plasma lipoprotein (a) level in the baboon.
AL White, JE Hixson, DL Rainwater… - Journal of Biological …, 1994 - Elsevier
High plasma levels of lipoprotein (a)(Lp (a)) and its unique apolipoprotein, apo (a), are an
independent risk factor for cardiovascular disease. Plasma Lp (a) levels vary over a 1000 …
independent risk factor for cardiovascular disease. Plasma Lp (a) levels vary over a 1000 …
Plasma lipoprotein (a) concentration is controlled by apolipoprotein (a)(apo (a)) protein size and the abundance of hepatic apo (a) mRNA in a cynomolgus monkey …
N Azrolan, D Gavish, JL Breslow - Journal of Biological Chemistry, 1991 - ASBMB
The cynomolgus macaque was used as a model to study lipoprotein (a)(Lp (a)). Antibodies
to Lp (a) were used in Ouchterlony and Western blot analysis to show that cynomolgus …
to Lp (a) were used in Ouchterlony and Western blot analysis to show that cynomolgus …
Molecular basis of an apolipoprotein [a] null allele: a splice sitemutation is associated with deletion of a single exon
LA Cox, C Jett, JE Hixson - Journal of lipid research, 1998 - ASBMB
Abstract Apolipoprotein [a](apo [a]), a unique component of atherogeniclipoprotein [a], is
highly polymorphic in human and nonhuman primates. Nullalleles, producing no detectable …
highly polymorphic in human and nonhuman primates. Nullalleles, producing no detectable …
The apolipoprotein (a) gene resides on human chromosome 6q26–27, in close proximity to the homologous gene for plasminogen
SL Frank, I Klisak, RS Sparkes, T Mohandas… - Human genetics, 1988 - Springer
Summary Apolipoprotein (a)[apo (a)], the glycoprotein associated with the lipoprotein (a)[Lp
(a)] subfraction of plasma lipoproteins, has been shown to exhibit heritable molecular weight …
(a)] subfraction of plasma lipoproteins, has been shown to exhibit heritable molecular weight …
Expressed hypervariable polymorphism of apolipoprotein (a).
MI Kamboh, RE Ferrell, BA Kottke - American journal of human …, 1991 - ncbi.nlm.nih.gov
Elevated plasma lipoprotein (a)(LP (a] levels are an independent predictor of the
development of premature atherosclerosis in humans. The LP (a) particle consists of two …
development of premature atherosclerosis in humans. The LP (a) particle consists of two …
[HTML][HTML] Hereditary and dietary effects on apolipoprotein [a] isoforms and Lp [a] in baboons.
DL Rainwater, GS Manis, JL VandeBerg - Journal of lipid research, 1989 - Elsevier
Baboons possess Lp [a] that is similar to human Lp [a], including the presence of the unique
protein, apo [a]. Baboon apo [a] occurred in at least nine isoforms distinguishable by size …
protein, apo [a]. Baboon apo [a] occurred in at least nine isoforms distinguishable by size …
Plasma lipoprotein (a) levels and expression of the apolipoprotein (a) gene are dependent on the nucleotide polymorphisms in its 5'-flanking region.
K Suzuki, M Kuriyama, T Saito… - The Journal of clinical …, 1997 - Am Soc Clin Investig
The apolipoprotein (a)(apo [a]) gene encodes a protein component of lipoprotein (a)[Lp (a)]
whose plasma levels vary widely among individuals. Hyper-Lp (a)-emia constitutes a risk …
whose plasma levels vary widely among individuals. Hyper-Lp (a)-emia constitutes a risk …
Polymorphic forms of human apolipoprotein [a]: inheritance and relationship of their molecular weights to plasma levels of lipoprotein [a].
JW Gaubatz, KI Ghanem, J Guevara, ML Nava… - Journal of Lipid …, 1990 - ASBMB
The plasma concentration of human lipoprotein [a], Lp [a], is highly correlated with coronary
artery disease. The protein moiety of Lp [a], apoLp [a], consists of two apoproteins, apo [a] …
artery disease. The protein moiety of Lp [a], apoLp [a], consists of two apoproteins, apo [a] …
Lipoprotein [a] in the chimpanezee: relationship of apo [a] phenotype to elevated plasma Lp [a] levels.
C Doucet, T Huby, J Chapman, J Thillet - Journal of lipid research, 1994 - ASBMB
Several studies have documented the presence of Lp [a] in nonhuman primates. However,
data are lacking in great apes such as the chimpanzee. We have studied the quantitative …
data are lacking in great apes such as the chimpanzee. We have studied the quantitative …
Lipoprotein (a) concentrations and phenotypes in controls and patients with hypercholesterolemia or hypertriglyceridemia
MM Ritter, HC Geiss, WO Richter, P Schwandt - Metabolism, 1994 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] concentrations are known to be stable under various dietary
and drug regimens. Little is known about the influence of hyperlipoproteinemia on Lp (a) …
and drug regimens. Little is known about the influence of hyperlipoproteinemia on Lp (a) …