Adenosine A2B and, much more importantly, adenosine A2A receptors modulate many
physiological and pathological processes in the brain. In this review, the most recent …

Adenosine acts in parallel as a neuromodulator and as a homeostatic modulator in the
central nervous system. Its neuromodulatory role relies on a balanced activation of inhibitory …

All biological tissues and bodily fluids include the autacoid adenosine. The P1 class of
purinergic receptors includes adenosine receptors. Four distinct G-protein-coupled …

Adenosine acts as a neurotransmitter in the brain through the activation of four specific G‐
protein‐coupled receptors (the A1, A2A, A2B, and A3 receptors). The A1 receptor has long …

Adenosine modulates several physiological functions in the CNS and in peripheral tissues
via membrane receptors which have been classified into four adenosine subtypes. A1 …

The adenosinergic system is involved in many important physiological functions. Adenosine
exerts its extracellular effects through four types of G-protein-coupled receptors: A1, A2A …

Of the four known adenosine receptors, the A2A receptor has received much attention over
the last few years. The discovery of high‐affinity and selective A2A adenosine receptor …

The adenosine A2A receptor subtype is one of the four adenosine receptors that have been
identified in the mammalian organism. In addition to being found in blood vessels, platelets …

Adenosine is a ubiquitous homeostatic substance released from most cells, including
neurones and glia. Once in the extracellular space, adenosine modifies cell functioning by …

Background: Alzheimer's disease (AD) is the most common form of dementia worldwide,
with approximately 6 million cases reported in America in 2020. The clinical signs of AD …