Design and engineering of nanogels for cancer treatment

MM Yallapu, M Jaggi, SC Chauhan - Drug discovery today, 2011 - Elsevier
Here, we provide a comprehensive insight into current advances in the use of nanogel-
mediated chemotherapy for cancer treatment. Nanogels are composed of cross-linked three …

Bioresponsive functional nanogels as an emerging platform for cancer therapy

D Huang, H Qian, H Qiao, W Chen… - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Bioresponsive nanogels with a crosslinked three-dimensional structure and an
aqueous environment that undergo physical or chemical changes including swelling and …

[HTML][HTML] Nanogels as target drug delivery systems in cancer therapy: A review of the last decade

AA Attama, PO Nnamani, OB Onokala… - Frontiers in …, 2022 - frontiersin.org
Cancer is an important cause of morbidity and mortality worldwide, irrespective of the level
of human development. Globally, it was estimated that there were 19.3 million new cases of …

Polymer nanogels: a versatile nanoscopic drug delivery platform

RT Chacko, J Ventura, J Zhuang… - Advanced drug delivery …, 2012 - Elsevier
In this review we put the spotlight on crosslinked polymer nanogels, a promising platform
that has the characteristics of an “ideal” drug delivery vehicle. Some of the key aspects of …

Multiresponsive nanogels for targeted anticancer drug delivery

Q Zhang, J Colazo, D Berg, SM Mugo… - Molecular …, 2017 - ACS Publications
Nanogels with a biomolecular coating (biocoating) were shown to be capable of triggered
delivery of anticancer drug Doxorubicin. The biocoating was formed utilizing binding …

Functional nanogels for biomedical applications

M Asadian-Birjand, A Sousa-Herves… - Current medicinal …, 2012 - ingentaconnect.com
This review addresses current and future perspectives of nanogel technology for
nanomedicine. The synthetic methodologies and material properties of nanogels prepared …

Hydrophobicity-adaptive nanogels for programmed anticancer drug delivery

H Yang, Q Wang, Z Li, F Li, D Wu, M Fan, A Zheng… - Nano Letters, 2018 - ACS Publications
Reconciling the conflicting needs for a prolonged circulation time, enhanced cellular uptake
by bulk tumor cells and cancer stem cells (CSCs), and extensive tumor tissue penetration …

[HTML][HTML] Nanogel: A versatile nano-delivery system for biomedical applications

Y Yin, B Hu, X Yuan, L Cai, H Gao, Q Yang - Pharmaceutics, 2020 - mdpi.com
Nanogel-based nanoplatforms have become a tremendously promising system of drug
delivery. Nanogels constructed by chemical crosslinking or physical self-assembly exhibit …

Doxorubicin-loaded composite nanogels for cancer treatment

M Mohammadi, L Arabi, M Alibolandi - Journal of Controlled Release, 2020 - Elsevier
Nanogels as a versatile vehicle for doxorubicin have attracted great attention during the last
decade. Since a nanogel composite device transport encapsulated drugs to the site of action …

Nanogel functionalization: a versatile approach to meet the challenges of drug and gene delivery

E Mauri, G Perale, F Rossi - ACS Applied Nano Materials, 2018 - ACS Publications
The design of nanostructures carrying therapeutic molecules represents the new frontier in
the biological and medical fields. In particular, researchers have identified nanogels as …