Reactivation of tumor suppressor genes (TSGs) involved in carcinogenesis by nontoxic
bioactive food component represents a promising strategy for cancer chemoprevention …

Breast cancer (BC) is the most common cancer among women and has high mortality rates.
Early detection is supposed to be critical for the patient's prognosis. In recent years, several …

Purpose: In order to investigate if aberrant promoter methylation of p16, BRCA1 and
RASSF1A genes contributes to biological behavior of triple-negative breast cancer (TNBC) …

Background Recently it has been suggested that acquisition of methylation of the BRCA1
promoter detectable in peripheral blood (PB) DNA, could give raise to development of breast …

We evaluated the promoter methylation levels of the APC, MGMT, h MLH1, RASSF1A and
CDKN2A genes in 107 colorectal cancer (CRC) samples and 80 healthy adjacent tissues …

Purpose DNA promoter hypermethylation of tumor suppressor genes is known to occur early
in cancer development, including breast cancer. To improve early breast cancer detection …

Trans-resveratrol, present in high concentration in the skin of red grapes and red wine, has a
dose-dependent antiproliferative effect in vitro, prevents the formation of mammary tumors …

Background: Oral tumor is a heterogeneous group of tumors, in which it has several different
histopathological and molecular features. Recently, genetic and epigenetic alterations are …

Background BRCA1 promoter methylation has been detected in DNA from peripheral blood
cells of both breast cancer patients and cancer-free females. However, the pathological …

Breast cancer is a multifactorial disease. It is the first cause of mortality per cancer for the
woman in the world (Jemal et al., 2011). The implication of specific genes, such as BRCA1 …