Synchronized discharge of populations of cortical neurons are often observed to underly
both the interictal spikes and tonic seizures generated in experimental epilepsy studies …

Jensen, Morten S. and Yoel Yaari. Role of intrinsic burst firing, potassium accumulation, and
electrical coupling in the elevated potassium model of hippocampal epilepsy. J …

The role of 'non-synaptic'mechanisms (ie those mechanisms that are independent of active
chemical synpases) in the synchronization of neuronal activity during seizures and their …

An understanding of the fundamental mechanisms underlying the development of epilepsy
and the generation of epileptic seizures will require delineation of the aberrant functional …

The degree of interdependence between intracranial EEG channels was investigated in four
epileptic patients with complex partial seizures of mesial temporal lobe origin. With a new …

1. We constructed model networks with 520 or 1,020 cells intended to represent the CA3
region of the hippocampus. Model neurons were simulated in enough detail to reproduce …

In the CA3 region of the hippocampus, pyramidal cells excite other pyramidal cells and
interneurons. The axons of CA3 pyramidal cells spread throughout most of the region to form …

1. We constructed a computer model of the in vitro CA3 region of the rat hippocampal slice
bathed in a high-potassium medium. Our aim was to understand better the mechanisms of …

It is now possible to develop a dynamic neuronal network model for generalized convulsive
seizures because of in vivo data recently obtained in a naturally occurring epilepsy model …

Epilepsy encompasses a diverse group of seizure disorders caused by a variety of
structural, cellular and molecular alterations of the brain primarily affecting the cerebral …