Inflammation is a critical driver of all stages of atherosclerosis, from lesion development to
plaque rupture. Cytokines are mediators of the immune response and in atherosclerosis, the …

Throughout the last two decades inflammation has been recognized as the central
mechanism underlying atherogenesis. A multitude of basic science work demonstrates the …

The concept of the involvement of inflammation in the pathogenesis of atherosclerosis has
existed since the 1800s, stemming from sentinel pathologic observations made by Rudolf …

Atherosclerotic coronary artery disease has a complex pathogenesis which extends beyond
cholesterol intimal infiltration. It involves chronic inflammation of the coronary artery wall …

Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …

Atherosclerosis represents the most common pathological substrate of coronary heart
disease (CHD), and the characterization of the disease as a chronic low-grade inflammatory …

Atherosclerosis is a dynamic, pathogenic process in the artery wall, with potential adverse
outcome for the host. Acute events such as myocardial infarction and ischemic stroke often …

Atherosclerosis and its complications are a major cause of morbidity and mortality worldwide
in spite of the improved medical and invasive treatment in terms of revascularization …

Atherosclerosis is a chronic inflammatory process and both the innate and adaptive immune
systems 1 play central roles in its initiation and subsequent progression. 2 Experimental …

Atherosclerosis, formerly considered a bland lipid storage disease, actually involves an
ongoing inflammatory response. Recent advances in basic science have established a …