Astrocytes form borders (glia limitans) that separate neural from non-neural tissue along
perivascular spaces, meninges and tissue lesions in the CNS. Transgenic loss-of-function …

Astrocytes are abundant glial cells in the central nervous system (CNS) that play active roles
in health and disease. Recent technologies have uncovered the functional heterogeneity of …

Astrocytes are crucial regulators of innate and adaptive immune responses in the injured
central nervous system. Depending on timing and context, astrocyte activity may exacerbate …

Astrocytes regulate fundamentally important functions to maintain central nervous system
(CNS) homeostasis. Altered astrocytic function is now recognized as a primary contributing …

Astrocytes control multiple processes in the nervous system in health and disease. It is now
clear that specific astrocyte subsets or activation states are associated with specific genomic …

Astrocytes are the most abundant cell type in the central nervous system (CNS), performing
complex functions in health and disease. It is now clear that multiple astrocyte subsets or …

Astrocytes play both physiological and pathological roles in maintaining central nervous
system (CNS) function. Here, we review the varied functions of astrocytes and how these …

Astrocyte heterogeneity is a rapidly evolving field driven by innovative techniques.
Inflammatory astrocytes, one of the first described subtypes of reactive astrocytes, are …

Astrocytes regulate neuroinflammatory responses after stroke and in other neurological
diseases. Although not all astrocytic responses reduce inflammation, their predominant …

Astrocytes play crucial roles in the brain and are involved in the neuroinflammatory
response. They become reactive in response to virtually all pathological situations in the …