Disturbances in skeletal muscle lipid metabolism may precede or contribute to the
development of whole body insulin resistance. In this study, we examined fasting and …

Introduction/hypothesis Disturbances in skeletal muscle fatty acid (FA) handling may
contribute to the development and progression of whole-body insulin resistance (IR). In this …

Altered skeletal muscle fatty acid (FA) metabolism contributes to insulin resistance. Here, we
compared skeletal muscle FA handling between subjects with impaired fasting glucose (IFG; …

Objective: An impaired fatty acid handling in skeletal muscle may be involved in the
development of insulin resistance and diabetes mellitus type 2 (DM2). We investigated …

Objective: In the metabolic syndrome (MetS), increased fat storage in 'nonadipose'tissues
such as skeletal muscle may be related to insulin resistance ('lipid overflow'hypothesis). The …

Background: Dietary fat quality may influence skeletal muscle lipid processing and fat
accumulation, thereby modulating insulin sensitivity. Objective: The objective was to …

Context: Increased adipose tissue lipolytic activity is considered an important factor in the
pathogenesis of skeletal muscle insulin resistance associated with obesity. Objective: The …

Background Although it is well-accepted that increased plasma free fatty acid (FFA)
concentration causes lipid overload and muscle insulin resistance in people with obesity …

Objective: To determine insulin sensitivity and skeletal muscle fatty acid (FA) handling at
baseline and after a high-fat mixed meal in impaired fasting glucose (IFG), impaired glucose …

A close relationship between elevated plasma free fatty acid (FFA) levels and insulin
resistance is commonly reported in obese subjects. The aim of the present study was to …