The molecules concerned with costimulation belong either to the immunoglobulin (Ig) or
tumor necrosis factor (TNF) superfamily. The tumor necrosis superfamily comprises …

Tumor necrosis factor (TNF) superfamily is a rapidly growing family of cytokines that interacts
with a corresponding superfamily of receptors. Liga-receptor interactions of this superfamily …

The tumor necrosis factor (TNF) ligand and cognate TNF receptor superfamilies constitute
an important regulatory axis that is pivotal for immune homeostasis and correct execution of …

Recent evidence shows that many molecules of the TNF family serve as counter-receptors,
inducing costimulation through reverse signals in addition to delivering signals through their …

The members of the tumour necrosis factor (TNF)/tumour necrosis factor receptor (TNFR)
superfamily are critically involved in the maintenance of homeostasis of the immune system …

Costimulatory signals initiated by the interaction between the tumor necrosis factor (TNF)
ligand and cognate TNF receptor (TNFR) superfamilies promote clonal expansion …

The proteins of the tumor necrosis factor (TNF) receptor superfamily are a group of cell-
surface receptors critically involved in the maintenance of homeostasis of the immune …

Signal transduction pathways which are initiated by the tumor necrosis factor (TNF) utilize
receptors which are devoid of intrinsic catalytic activity. Recently identified two families of …

The TNF receptor superfamily members are all type I membrane glycoproteins with typical
homology in the extracellular domain of variable numbers of cysteine-rich repeats (overall …

The tumor necrosis factor (TNF) receptor family contains death receptors, which have a
cytoplasmic death domain and can induce apoptosis, as well as receptors with no apparent …