Sex differences in neurodevelopmental and neurodegenerative disorders: focus on microglial function and neuroinflammation during development

R Hanamsagar, SD Bilbo - The Journal of steroid biochemistry and …, 2016 - Elsevier
Several neurological conditions are associated with sex differences in prevalence or
outcome. For example, autism predominantly affects boys, depression is more common in …

[HTML][HTML] The neuroendocrine female brain: from normal reproductive function to disease

MSB Silva, VM Navarro, K Chachlaki - Frontiers in Neuroscience, 2023 - frontiersin.org
Reproductive function is often associated only with the gonads, both male and female, which
work together for the sole purpose of procreating, according to lay perception and …

Estrogen regulates myogenic tone in hippocampal arterioles by enhanced basal release of nitric oxide and endothelial SKCa channel activity

DA Jeffrey, A Russell, M Bueno Guerrero, JT Fontaine… - bioRxiv, 2023 - biorxiv.org
Arteries and arterioles exhibit myogenic tone, a partially constricted state that allows further
constriction or dilation in response to moment-to-moment fluctuations in blood pressure. The …

Sexual differentiation of the rodent brain: dogma and beyond

KM Lenz, BM Nugent, MM McCarthy - Frontiers in neuroscience, 2012 - frontiersin.org
Steroid hormones of gonadal origin act on the neonatal brain to produce sex differences that
underlie adult reproductive physiology and behavior. Neuronal sex differences occur on a …

[HTML][HTML] Sex steroids, adult neurogenesis, and inflammation in CNS homeostasis, degeneration, and repair

TA Larson - Frontiers in endocrinology, 2018 - frontiersin.org
Sex steroidal hormones coordinate the development and maintenance of tissue architecture
in many organs, including the central nervous systems (CNS). Within the CNS, sex steroids …

Gender and sex—time to bridge the gap

GP Dotto - EMBO molecular medicine, 2019 - embopress.org
Interdisciplinary research and education are key for a better appreciation of sex and gender
as defining a person, and for novel societal and personalized health-care approaches …

Normal and abnormal cerebrovascular development: gene–environment interactions during early life with later life consequences

MS Scher - Handbook of clinical neurology, 2013 - Elsevier
A greater understanding of cerebrovascular health and disease requires the consideration
of recent neuroscience advances concerning neuroplasticity in the context of classical …

Sex: a significant risk factor for neurodevelopmental and neurodegenerative disorders

P Pinares-Garcia, M Stratikopoulos, A Zagato, H Loke… - Brain sciences, 2018 - mdpi.com
Males and females sometimes significantly differ in their propensity to develop neurological
disorders. Females suffer more from mood disorders such as depression and anxiety …

Sex differences in the brain: focus on developmental mechanisms

MM McCarthy - Principles of Gender-Specific Medicine, 2023 - Elsevier
Pervasive gender inequities in the frequency and severity of neurologic and
neuropsychiatric disorders remain unexplained. The complexity of humans precludes ready …

Sex differences in associations between white matter microstructure and gonadal hormones in children and adolescents with prenatal alcohol exposure

KA Uban, MM Herting, JR Wozniak, ER Sowell… - …, 2017 - Elsevier
Despite accumulating evidence from animal models demonstrating that prenatal alcohol
exposure (PAE) results in life-long neuroendocrine dysregulation, very little is known on this …