The current state of treatment and future directions in cutaneous malignant melanoma

M Ernst, A Giubellino - Biomedicines, 2022 - mdpi.com
Malignant melanoma is the leading cause of death among cutaneous malignancies. While
its incidence is increasing, the most recent cancer statistics show a small but clear decrease …

[HTML][HTML] Melanoma immunotherapy dominates the field

P Diamantopoulos, H Gogas - Annals of translational medicine, 2016 - ncbi.nlm.nih.gov
The incidence of melanoma is increasing worldwide and despite early detection and
intervention, the number of patients dying from metastatic disease continues to rise. The …

Systemic therapy of metastatic melanoma: on the road to cure

J Steininger, FF Gellrich, A Schulz, D Westphal… - Cancers, 2021 - mdpi.com
Simple Summary Malignant melanoma is more dangerous than most other skin cancers due
to its ability to spread early and aggressively. Until the development of new therapeutic …

Emerging strategies in systemic therapy for the treatment of melanoma

PA Ascierto, K Flaherty, S Goff - American Society of Clinical …, 2018 - ascopubs.org
Recent years have seen major improvements in survival of patients with advanced
melanoma with the advent of various novel systemic immunotherapies and targeted …

Current and future roles of targeted therapy and immunotherapy in advanced melanoma

AJ Olszanski - Journal of Managed Care Pharmacy, 2014 - jmcp.org
BACKGROUND: Melanoma is an aggressive disease that accounts for approximately 75%
of skin cancer-related deaths. Historically, treatment options for patients with advanced …

Immunotherapy for advanced melanoma: fulfilling the promise

H Gogas, A Polyzos, J Kirkwood - Cancer treatment reviews, 2013 - Elsevier
The incidence of melanoma is increasing worldwide and despite early detection and
intervention, the number of patients dying from metastatic disease continues to rise. The …

Immunotherapy of melanoma

C Bender, JC Hassel, A Enk - Oncology research and treatment, 2016 - karger.com
Arising from melanocytes in skin, mucosal membranes, eye, and meninges, melanoma is a
tumor that has been associated with poor prognosis in advanced disease stages. Given the …

Therapeutic advancements across clinical stages in melanoma, with a focus on targeted immunotherapy

C Trojaniello, JJ Luke, PA Ascierto - Frontiers in Oncology, 2021 - frontiersin.org
Melanoma is the most fatal skin cancer. In the early stages, it can be safely treated with
surgery alone. However, since 2011, there has been an important revolution in the treatment …

Novel targets for the treatment of melanoma

L Ambrosi, S Khan, RD Carvajal, J Yang - Current oncology reports, 2019 - Springer
Abstract Purpose of Review In this article, we will briefly review the current treatment
landscape for metastatic melanoma and provide a comprehensive update on emerging …

Advances in targeting cutaneous melanoma

D Kasakovski, M Skrygan, T Gambichler, L Susok - Cancers, 2021 - mdpi.com
Simple Summary Cutaneous Melanoma (CM), arising from pigment-producing melanocytes
in the skin, is an aggressive cancer with high metastatic potential. While cutaneous …