Simple Summary Cutaneous Melanoma (CM), arising from pigment-producing melanocytes
in the skin, is an aggressive cancer with high metastatic potential. While cutaneous …

Melanoma is the most aggressive and deadly type of skin cancer and is known for its poor
prognosis as soon as metastasis occurs. Since 2011, new and effective therapies for …

Metastatic melanoma is the most aggressive and obstinate skin cancer with poor prognosis.
Variant novel applicable regimens have emerged during the past decades intensively, while …

The incidence of malignant melanoma is increasing rapidly on a global scale. Although
some types of melanoma, for example primary cutaneous melanoma, can be managed by …

Cutaneous melanoma remains a severe public health threat, with annual incidence
increasing slowly but steadily over 4 decades. While early-stage melanomas can typically …

Simple Summary Progress in the treatment of malignant melanoma, particularly with the use
of immunotherapy, has markedly improved outcomes. Despite these successes, many …

Melanoma is the deadliest form of skin cancer being responsible for 80% of skin cancer
deaths. Furthermore, the incidence of metastatic melanoma has increased over the past …

Cutaneous melanoma is the main cause of death for skin cancer. The majority of patients
with a diagnosis of melanoma have localized disease, which can be successfully treated …

Simple Summary The introduction of immune checkpoint inhibitors and targeted therapy for
the treatment of unresectable advanced or metastatic melanoma has changed the prognosis …

Over the past several years, management of advanced melanoma has been transformed by
the development and approval of novel therapeutic approaches. Genetically targeted …