The recent discovery that an additional estrogen receptor (ERβ) subtype is present in many
rat, mouse, and human tissues has advanced our understanding of the mechanisms …

Estrogen receptors, comprised of ERα and ERβ isoforms in mammals, act as
ligandmodulated transcription factors and orchestrate a plethora of cellular functions from …

The estrogen-related receptor α gene encodes a nuclear receptor protein, ERRα, whose
structure is closely related to the estrogen receptors. ERRα modulates estrogen receptor …

Estrogens and selective estrogen receptor modulators (SERMs) interact with estrogen
receptor (ER) α and β to activate or repress gene transcription. To understand how …

Estrogens and selective estrogen receptor modulators (SERMs) interact with estrogen
receptor (ER) α and β to activate or repress gene transcription. To understand how …

Estrogen receptors (ERs1) are ligand-activated transcription factors that belong to the
nuclear hormone receptor superfamily. In the late 1950s, the existence of a receptor …

Estrogens elicit many biomedically important responses in different target tissues, and the
respective roles of the two estrogen receptors, ERα and ERβ, in mediating these bioactivities …

The biological effects of the steroid hormone, estradiol, are largely mediated by estrogen
receptor (ER) proteins within the nuclei of target cells. The ER protein exists in two known …

Estrogen receptors beta (ERβ) belong to the nuclear receptor superfamily of ligand-
dependent transcription factors that play critical roles in regulating genes involved in a wide …

Estrogen signaling is mediated by estrogen receptors α (ERα) and β (ERβ). Although a
consensus has now been reached concerning many physiological functions of ERα, those of …