1. Central effects of single doses of captopril (12.5, 25 and 50 mg) were studied in fourteen
healthy male subjects. Two placebos and an active control drug, oxazepam (15 mg), were …

1. Effects of single doses of captopril (12.5, 25 and 50 mg) on the electroencephalogram
(EEG) and on body sway were studied in fourteen healthy male subjects. Oxazepam (15 …

A small double-blind pilot study was carried out to assess whether captopril treatment in
hypertension has a euphoriant effect. Eight patients were maintained on constant therapy of …

Captopril (50 mg orally) produced a significant fall in systolic and diastolic blood pressure in
six normotensive sodium replete subjects, without a rise in heart rate. On captopril, there …

1 The effect of captopril on autonomic reflex functions has been investigated in fifteen
patients with essential hypertension by examining their responses to tests of baroreceptor …

1. Measures of memory, information processing ability, mood states and trait anxiety were
estimated in a double‐blind, double‐dummy, randomised cross‐over trial which compared …

1 The effects of the orally active angiotensin converting enzyme inhibitor, captopril, were
examined in 15 patients with mild or moderate essential hypertension. 2 Following initial …

Captopril, an angiotensin-converting enzyme inhibitor, is currently utilized in the treatment of
hypertension. In recent years, there have been several reports of behavioral changes …

1 The methodology and interim results of a post marketing surveillance of captopril, the first
orally active angiotensin converting enzyme inhibitor are presented. 2 Utilising viewdata …

The results of early clinical trials of the orally active angiotensin converting enzyme inhibitor,
Captopril, in mild, moderate and severe hypertension demonstrate that the compound is …