Nuclear RNA Turnover: Cell Skip to Main Content Advertisement Cell This journal offers
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RNA decay plays a crucial role in post-transcriptional regulation of gene expression. Work
conducted over the last decades has defined the major mRNA decay pathways, as well as …

RNA turnover is an integral part of cellular RNA homeostasis and gene expression
regulation. Whereas the cytoplasmic control of protein-coding mRNA is often the focus of …

The control of mRNA turnover is essential for the cell to rationalize its mRNA content both
under physiological conditions and upon stress. Several mechanisms involved in the control …

RNA decay plays a major role in regulating gene expression and is tightly networked with
other aspects of gene expression to effectively coordinate post-transcriptional regulation …

RNA decay is crucial for mRNA turnover and surveillance and misregulated in many
diseases. This complex system is challenging to study, particularly in mammals, where it …

Multiple mechanisms have evolved to regulate the eukaryotic genome. We have identified
CTN-RNA, a mouse tissue-specific∼ 8 kb nuclear-retained poly (A)+ RNA that regulates the …

The levels of cellular messenger RNA transcripts can be regulated by controlling the rate at
which the mRNA decays. Because decay rates affect the expression of specific genes, they …

In this perspective, we discuss the regulatory impact of nuclear RNA export and decay on
messenger RNA (mRNA) functionality. It is well established that control of protein-coding …

In budding yeast, the nuclear RNA surveillance system is active on all pre-mRNA transcripts
and modulated by nutrient availability. To test the role of nuclear surveillance in …