A novel dosage form with dose-adjusting and swallow-assisting functions, named “xerogel
pills,” was developed for pediatric or geriatric patients. It is a multiple-unit dosage form in …

The xerogel pill has been developed as a novel dosage form with dose-adjusting and
swallow-assisting functions by using drop freeze-drying (DFD) technique. It was double …

The “xerogel pill” composed of an inner drug core and an outer dried-gel layer has been
developed in our previous work. The aim of this study was to characterize the …

A dry elixir containing drug elixir in wall-forming materials as a novel oral dosage form was
developed using the spray-drying technique. Poorly water-soluble flurbiprofen (FP) was …

The aim of this study was to prepare an oral formulation that is easy to take. We investigated
the preparation of mini-tablets that are solid with moderate strength during storage but swell …

Orodispersible films (ODFs) are an advantageous dosage form to accomplish patient
convenience and compliance in oral drug delivery. They provide a number of special …

Prolonged drug release provided by multiple-unit dosage forms is highly beneficial to
enhance the compliance and safety of the pharmacotherapy even for patients with …

To develop an attractive formulation platform for the continuous production of directly
compressible powders. This could have improved compressibility and compatibility …

Spray freeze-drying (SFD) technique using four-fluid nozzle (4N), which is a novel particle
design technique previously developed by authors, has been further developed to expand …

Dysphagia refers to difficulty swallowing certain foods, liquids, or pills. It is common among
the elderly with chronic diseases who need to take drugs for long periods. Therefore …