Sepsis induces lymphocyte apoptosis and prevention of lymphocyte death may improve the
chances of surviving this disorder. We compared the efficacy of a selective caspase-3 …

The role of lymphocyte apoptosis in septic shock remains a controversial issue. Using
Annexin V and flow cytometry analysis on freshly isolated cells, we evaluated circulating …

The molecular mechanisms of immune cell apoptosis during sepsis remain unclear. Two
young adult baboons (Papio sp.) received a lethal dose of live Escherichia coli and were …

Dysregulated cell death in several tissues is intimately involved in the pathogenesis of
sepsis and contributes to multiple organ failure. Whether cell death during sepsis occurs by …

Despite numerous advances in intensive care medicine, sepsis remains a deadly disease.
Today, conventional therapeutic approaches and mainstream scientific research mostly …

It has recently been appreciated that patients with severe sepsis and septic shock suffer from
altered innate and adaptive immune responses, leading to an impaired clearance of …

Objectives To determine if apoptosis (programmed cell death) occurs systemically in
lymphoid and parenchymal cells during sepsis. To examine the potential role of T and B …

Sepsis is a life-threatening illness that occurs due to an abnormal host immune network
which extends through the initial widespread and overwhelming inflammation, and …

Surgical injury can be a life‐threatening complication, not only due to the injury itself, but
also due to immune responses to the injury and subsequent development of infections …

Introduction: Over the last two decades, many of the mechanisms underlying the
pathophysiology of sepsis have been uncovered, but this has not led to the development of …