Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
responses to infection (Third International Consensus definition for Sepsis and septic …

Despite the rapid development and many significant advances in preventive methods and
clinical care, trauma remains the most common cause of mortality during the first thirty years …

Lymphocyte cell death contributes to sepsis‐induced immunosuppression, leading to poor
prognosis. This study examined whether sepsis severity and beta‐blocker therapy could …

An excessive inflammatory response accompanies the initial stages of severe infection and
appears to contribute to associated organ system failure and death [1, 2, 3]. A number of …

Sepsis remains one of the leading causes of mortality in critically ill patients. Increased
insight into the complexities of this disease process has resulted in the targeting of various …

Sepsis causes lymphopenia which is inversely correlated with patient survival. The role of
apoptosis-specific immune-activation and activation-induced cell-death in sepsis is …

Sepsis remains the leading cause of death in the ICU. Considering the key role of the
immune system in sepsis, immunomodulation represents an attractive target for adjunctive …

Inflammatory cells, in particular monocytes/macrophages, release pro-inflammatory
mediators in response to several infectious and non-infectious stimuli. The excessive …

Sepsis is an infection-initiated systemic inflammatory syndrome with an estimated incidence
of 18 million cases annually worldwide. Despite advances in intensive care and supportive …

Sepsis, a life threating syndrome characterized by organ failure after infection, is the most
common cause of death in hospitalized patients. The treatment of sepsis is generally …