Clinical evidence and potential neurobiological underpinnings of unresolved symptoms of depression.
MH Trivedi, E Hollander, D Nutt… - Journal of Clinical …, 2008 - psychiatrist.com
Objective: Recent data indicate that more than 65% of patients with major depressive
disorder (MDD) fail to achieve remission. This article reviews research on the current …
disorder (MDD) fail to achieve remission. This article reviews research on the current …
Major depressive disorder: understanding the significance of residual symptoms and balancing efficacy with tolerability
L Culpepper, PR Muskin, SM Stahl - The American journal of medicine, 2015 - Elsevier
Introduction Major depressive disorder is a complex and frequent psychiatric condition that
poses significant challenges to both the patients who experience it and the physicians who …
poses significant challenges to both the patients who experience it and the physicians who …
Residual symptoms in depression: can treatment be symptom-specific?
M Menza, H Marin, RS Opper - Journal of Clinical Psychiatry, 2003 - psychiatrist.com
Background: Most patients with depression continue to have symptoms after treatment. It is
well documented that these “residual” symptoms are common and are associated with …
well documented that these “residual” symptoms are common and are associated with …
Prevalence and outcome of partial remission in depression
R Tranter, C O'Donovan, P Chandarana… - Journal of Psychiatry and …, 2002 - jpn.ca
The goal of treatment of major depression should be full remission. Many patients, however,
fail to achieve or maintain symptom-free status. Residual depressive symptoms are …
fail to achieve or maintain symptom-free status. Residual depressive symptoms are …
[HTML][HTML] Residual symptoms in major depressive disorder: prevalence, effects, and management
J Zajecka, SG Kornstein, P Blier - The Primary Care Companion for …, 2013 - psychiatrist.com
Patients with major depressive disorder (MDD) who have responded to or remitted from
antidepressant treatment frequently have persistent residual symptoms (eg, fatigue, sleep …
antidepressant treatment frequently have persistent residual symptoms (eg, fatigue, sleep …
Strategies to enhance the therapeutic efficacy of antidepressants: targeting residual symptoms
BT Kurian, TL Greer, MH Trivedi - Expert review of …, 2009 - Taylor & Francis
Major depressive disorder (MDD) is an illness of great morbidity that affects many people
across the world. The current goal for treatment of MDD is to achieve remission (ie, no …
across the world. The current goal for treatment of MDD is to achieve remission (ie, no …
Major depressive disorder: a prospective study of residual subthreshold depressive symptoms as predictor of rapid relapse
LL Judd, HS Akiskal, JD Maser, PJ Zeller… - Journal of affective …, 1998 - Elsevier
Background: The study tested whether level of recovery from major depressive episodes
(MDEs) predicts duration of recovery in unipolar major depressive disorder (MDD) patients …
(MDEs) predicts duration of recovery in unipolar major depressive disorder (MDD) patients …
A new empirical definition of major depressive episode recovery and its positive impact on future course of illness
LL Judd, PJ Schettler, AJ Rush… - The Journal of …, 2016 - psychiatrist.com
Objective: To provide the first head-to-head test of the predictive validity of 2 resolution
levels included in the current consensus definition of major depressive episode (MDE) …
levels included in the current consensus definition of major depressive episode (MDE) …
Partial remission, residual symptoms, and relapse in depression
ES Paykel - Dialogues in clinical neuroscience, 2008 - Taylor & Francis
Partial remission from depression, with residual symptoms, is an important problem in
depression. This paper reviews the frequency and features of this outcome, and its …
depression. This paper reviews the frequency and features of this outcome, and its …
Residual symptoms in depression: an emerging therapeutic target
GA Fava, S Fabbri, N Sonino - Progress in Neuro-Psychopharmacology and …, 2002 - Elsevier
Residual symptoms, despite successful response to therapy, appear to be the rule in
unipolar depression. Most of the residual symptoms occur in the prodromal phase of illness …
unipolar depression. Most of the residual symptoms occur in the prodromal phase of illness …