Objective: Recent data indicate that more than 65% of patients with major depressive
disorder (MDD) fail to achieve remission. This article reviews research on the current …

Introduction Major depressive disorder is a complex and frequent psychiatric condition that
poses significant challenges to both the patients who experience it and the physicians who …

Background: Most patients with depression continue to have symptoms after treatment. It is
well documented that these “residual” symptoms are common and are associated with …

The goal of treatment of major depression should be full remission. Many patients, however,
fail to achieve or maintain symptom-free status. Residual depressive symptoms are …

Patients with major depressive disorder (MDD) who have responded to or remitted from
antidepressant treatment frequently have persistent residual symptoms (eg, fatigue, sleep …

Major depressive disorder (MDD) is an illness of great morbidity that affects many people
across the world. The current goal for treatment of MDD is to achieve remission (ie, no …

Background: The study tested whether level of recovery from major depressive episodes
(MDEs) predicts duration of recovery in unipolar major depressive disorder (MDD) patients …

Objective: To provide the first head-to-head test of the predictive validity of 2 resolution
levels included in the current consensus definition of major depressive episode (MDE) …

Partial remission from depression, with residual symptoms, is an important problem in
depression. This paper reviews the frequency and features of this outcome, and its …

Residual symptoms, despite successful response to therapy, appear to be the rule in
unipolar depression. Most of the residual symptoms occur in the prodromal phase of illness …