Objectives: This study investigated adherence to drug therapy guidelines in heart failure
(HF) with reduced left-ventricular ejection fraction (LVEF) of< 40%(heart failure with reduced …

The syndrome of heart failure (HF) has historically been dichotomized based on clinical trial
inclusion criteria into patients with a reduced or preserved left ventricular ejection fraction …

Background: Guidelines strongly recommend patients with heart failure with reduced
ejection fraction (HFrEF) be treated with multiple medications proven to improve clinical …

The treatment of heart failure with reduced ejection fraction (HFrEF) has changed
considerably over time, particularly with the sequential development of therapies aimed at …

Aims In older patients, guideline‐directed medical therapy (GDMT) for heart failure (HF) with
reduced ejection fraction (< 40%; HFrEF) is not contraindicated, but adherence to guidelines …

Background Physicians' adherence to guideline‐recommended therapy is associated with
short‐term clinical outcomes in heart failure (HF) with reduced ejection fraction (HFrEF) …

Objectives This study evaluated the impact of clinical and physiological factors limiting
treatment optimization toward recommended medical therapy in heart failure (HF) …

Aims To evaluate how recommendations of European guidelines regarding
pharmacological and non‐pharmacological treatments for heart failure (HF) are adopted in …

Background: Guidelines recommend that patients with heart failure with reduced ejection
fraction (HFrEF) have medical therapy titrated to target doses derived from clinical trials, as …

In this update of the Canadian Cardiovascular Society heart failure (HF) guidelines, we
provide comprehensive recommendations and practical tips for the pharmacologic …