Deciphering the Model Pathogenic Fungus Cryptococcus Neoformans

A Idnurm, YS Bahn, K Nielsen, X Lin… - Nature Reviews …, 2005 - nature.com
Cryptococcus neoformans is a basidiomycete fungal pathogen of humans that has diverged
considerably from other model fungi such as Neurospora crassa, Aspergillus nidulans …

Genetics of Cryptococcus neoformans

CM Hull, J Heitman - Annual review of genetics, 2002 - annualreviews.org
▪ Abstract Cryptococcus neoformans is a pathogenic fungus that primarily afflicts
immunocompromised patients, infecting the central nervous system to cause …

Recent Evolution of the Human Pathogen Cryptococcus neoformans by Intervarietal Transfer of a 14-Gene Fragment

LA Kavanaugh, JA Fraser… - Molecular biology and …, 2006 - academic.oup.com
The availability of the whole-genome sequence from the 2 known varieties of the human
pathogenic fungus Cryptococcus neoformans provides an opportunity to study the relative …

Recapitulation of the Sexual Cycle of the Primary Fungal Pathogen Cryptococcus neoformans var. gattii: Implications for an Outbreak on Vancouver Island, Canada

JA Fraser, RL Subaran, CB Nichols, J Heitman - Eukaryotic cell, 2003 - Am Soc Microbiol
Cryptococcus neoformans is a human fungal pathogen that exists as three distinct varieties
or sibling species: the predominantly opportunistic pathogens C. neoformans var …

Profiling a killer, the development of Cryptococcus neoformans

L Kozubowski, J Heitman - FEMS microbiology reviews, 2012 - academic.oup.com
The ability of fungi to transition between unicellular and multicellular growth has a profound
impact on our health and the economy. Many important fungal pathogens of humans …

Multiple gene genealogies reveal recent dispersion and hybridization in the human pathogenic fungus Cryptococcus neoformans

J Xu, R Vilgalys, TG Mitchell - Molecular Ecology, 2000 - Wiley Online Library
Cryptococcus neoformans (= Filobasidiella neoformans) is a significant emerging fungal
pathogen of humans. To understand the evolution of this pathogen, 34 strains were obtained …

The Genome of the Basidiomycetous Yeast and Human Pathogen Cryptococcus neoformans

BJ Loftus, E Fung, P Roncaglia, D Rowley, P Amedeo… - Science, 2005 - science.org
Cryptococcus neoformans is a basidiomycetous yeast ubiquitous in the environment, a
model for fungal pathogenesis, and an opportunistic human pathogen of global importance …

The Biology of the Cryptococcus neoformans Species Complex

X Lin, J Heitman - Annu. Rev. Microbiol., 2006 - annualreviews.org
Cryptococcus neoformans is a major cause of fungal meningoencephalitis in
immunocompromised patients. Despite recent advances in the genetics and molecular …

[HTML][HTML] Recognition of seven species in the Cryptococcus gattii/Cryptococcus neoformans species complex

F Hagen, K Khayhan, B Theelen, A Kolecka… - Fungal genetics and …, 2015 - Elsevier
Phylogenetic analysis of 11 genetic loci and results from many genotyping studies revealed
significant genetic diversity with the pathogenic Cryptococcus gattii/Cryptococcus …

[HTML][HTML] The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans

JN Steenbergen, A Casadevall - Microbes and infection, 2003 - Elsevier
The origin of virulence in environmental fungi that have no requirement for animal hosts in
their life cycle is enigmatic. Cryptococcus neoformans is a human pathogenic fungus with …