Medicinal perspective of indole derivatives: recent developments and structure-activity relationship studies
Heterocyclic compounds play a significant role in various biological processes of the human
body and many of them are in clinical use due to their diverse, chemical and biological …
body and many of them are in clinical use due to their diverse, chemical and biological …
Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives
A Kumari, RK Singh - Bioorganic chemistry, 2019 - Elsevier
Indole is a versatile pharmacophore, a privileged scaffold and an outstanding heterocyclic
compound with wide ranges of pharmacological activities due to different mechanisms of …
compound with wide ranges of pharmacological activities due to different mechanisms of …
Recent progress of bioactivities, mechanisms of action, total synthesis, structural modifications and structure-activity relationships of indole derivatives: a review
T Li, H Xu - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
Indole (2, 3-benzopyrrole) containing a pyrrolyl ring possesses the characteristic of electron-
rich aromatic compounds. Indole occurs in the oil of jasmine and cloves and coal tar …
rich aromatic compounds. Indole occurs in the oil of jasmine and cloves and coal tar …
The Multi‐Pharmacological Targeted Role of Indole and its Derivatives: A review
B Suliphuldevara Mathada… - …, 2023 - Wiley Online Library
Heterocycles are a privileged motif that appears as a momentous objective in medicinal
chemistry. An important class of compounds for drug discovery and design is indole and its …
chemistry. An important class of compounds for drug discovery and design is indole and its …
Development and application of indolines in pharmaceuticals
H Wei, B Li, N Wang, Y Ma, J Yu, X Wang, J Su… - …, 2023 - Wiley Online Library
In recent years, the incidence of cancer is high around the world, and the resistance of
bacteria is increasing. To cope with the potentially adverse side effects of cancer …
bacteria is increasing. To cope with the potentially adverse side effects of cancer …
Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view
N Chadha, O Silakari - European Journal of Medicinal Chemistry, 2017 - Elsevier
Indoles constitute extensively explored heterocyclic ring systems with wide range of
applications in pathophysiological conditions that is, cancer, microbial and viral infections …
applications in pathophysiological conditions that is, cancer, microbial and viral infections …
An insight into the medicinal perspective of synthetic analogs of indole: A review
PV Thanikachalam, RK Maurya, V Garg… - European journal of …, 2019 - Elsevier
Heterocycles occupy a salient place in chemistry due to their wide range of activity in the
fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, indole …
fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, indole …
Biomedical importance of indoles
The indole nucleus is an important element of many natural and synthetic molecules with
significant biological activity. This review covers some of the relevant and recent …
significant biological activity. This review covers some of the relevant and recent …
A brief review of the biological potential of indole derivatives
S Kumar, Ritika - Future Journal of Pharmaceutical Sciences, 2020 - Springer
Background Various bioactive aromatic compounds containing the indole nucleus showed
clinical and biological applications. Indole scaffold has been found in many of the important …
clinical and biological applications. Indole scaffold has been found in many of the important …
[PDF][PDF] Indole: the molecule of diverse biological activities
S Biswal, U Sahoo, S Sethy, HKS Kumar… - Asian J. Pharm. Clin …, 2012 - researchgate.net
ABSTRACT A large number of efforts were made to synthesize different heterocyclic
compounds and their derivatives in the past decade and were found to posses promising …
compounds and their derivatives in the past decade and were found to posses promising …