BACKGROUND: Very limited information has been published regarding cardiac apoptosis in
menopausal women or in those after bilateral oophorectomy. The purpose of this study was …

To determine whether apoptotic and necrotic myocyte cell death occur acutely and
chronically after infarction, the formation of DNA strand breaks and the localization of myosin …

In this issue of Circulation Research, Guerra and col-leagues1 report that myocyte death in
the failing human heart is gender dependent. This work is in continuation of Dr Anversa's …

Background Loss of myocytes is an important mechanism in the development of cardiac
failure of either ischemic or nonischemic origin. However, whether programmed cell death …

Aims We examined cardiomyocyte apoptosis in chronic heart failure (HF) and its possible
link to elevated wall stress. Methods and results Moderate HF was produced in sheep by …

Objective: Recently, deletion of specific genes by so called knock‐out techniques has
become important for investigating the pathogenesis of various diseases. This form of …

Changes in oxidative stress and apoptotic process were studied during the progression of a
compensated hypertrophy to a decompensated heart failure in guinea pigs. Banding of the …

It has been reported that apoptosis is a significant contributor to myocardial cell death as a
result of reperfusion injury. However, whether the extent of cardiomyocyte apoptosis …

Background. This study investigated histopathological changes and apoptotic factors that
may be involved in the renal damage caused by congestive heart failure in a rat model of …

The effect of prolonged hypoxia as well as the molecular mechanisms on cardiac cell death
is not well established. A possible role of Bcl-2 and Bax in hypoxia-induced apoptosis in …