Introduction The aetiology of acute exacerbations of chronic obstructive pulmonary disease
(COPD) remains incompletely understood and strategies for treatment and prevention have …

Exacerbations of chronic obstructive pulmonary disease (COPD) are episodes of acute
worsening of respiratory symptoms that require additional therapy. These events play a …

Background Unfortunately, many COPD patients continue to exacerbate despite good
adherence to GOLD Class D recommended therapy. Acute exacerbations lead to an …

COPD exacerbations are associated with worsening symptoms including cough, shortness
of breath, sputum production and airflow obstruction. Increased numbers of exacerbations …

Introduction Considering the role of bacteria in the onset of acute exacerbation of COPD
(AECOPD), we hypothesized that the use of influenza-Streptococcus pneumoniae …

COPD patients have alterations in their lung microbiome that may result in chronic infection
with potentially pathogenic microorganisms (PPMs) even in periods of clinical stability and …

Chronic obstructive pulmonary disease (COPD) is the most common chronic respiratory
condition in adults and is characterized by progressive airflow limitation that is not fully …

Background Alterations in the composition of the lung microbiome associated with adverse
clinical outcomes, known as dysbiosis, have been implicated with disease severity and …

Background Antibiotic-resistant strains of pathogenic bacteria are increasingly prevalent in
hospitals and the community. Acute exacerbations of COPD (AE-COPD) often result in …

Microorganisms, particularly bacteria, are frequently found in the lower airways of COPD
patients, both in stable state and during exacerbations. The host–pathogen relationship in …