Diagnosis and treatment of gastrointestinal dysfunction in hereditary TTR amyloidosis

L Obici, OB Suhr - Clinical Autonomic Research, 2019 - Springer
Purpose To review the management of gastrointestinal symptoms in patients with hereditary
transthyretin amyloidosis, discussing diagnostic evaluations, assessment of disease …

[PDF][PDF] Gastrointestinal manifestations in hereditary transthyretin amyloidosis: a single-centre experience

M Luigetti, A Tortora, A Romano… - J. Gastrointest. Liver …, 2020 - academia.edu
ABSTRACT Background & Aims: Hereditary transthyretin (ATTRv) amyloidosis represents a
diagnostic challenge considering the great variability in clinical presentation and multiorgan …

Recommendations for the diagnosis and management of transthyretin amyloidosis with gastrointestinal manifestations

R Nakov, OB Suhr, G Ianiro, J Kupcinskas… - European journal of …, 2021 - journals.lww.com
Transthyretin amyloid (ATTR) amyloidosis is an adult-onset, rare systemic disorder
characterized by the accumulation of misfolded fibrils in the body, including the peripheral …

Management of gastrointestinal complications in hereditary transthyretin amyloidosis: a single-center experience over 40 years

J Wixner, OB Suhr, I Anan - Expert Review of Gastroenterology & …, 2018 - Taylor & Francis
ABSTRACT Introduction: Hereditary transthyretin amyloidosis (ATTRm amyloidosis) is a rare
disease caused by the deposition and accumulation of insoluble non-native transthyretin …

[PDF][PDF] Transthyretin Amyloidosis with Gastrointestinal Manifestation

R Nakov, S Sarafov, V Nakov… - J Gastrointestin …, 2019 - pdfs.semanticscholar.org
Transthyretin amyloidosis (ATTR) is a rare, progressive, life-threatening, hereditary disorder
caused by mutations in the transthyretin gene. Due to the phenotypic heterogeneity, ATTR is …

Gastric emptying in hereditary transthyretin amyloidosis: the impact of autonomic neuropathy

J Wixner, P Karling, A Rydh, R Hörnsten… - …, 2012 - Wiley Online Library
Background Gastrointestinal (GI) complications are common in hereditary transthyretin
amyloidosis and an autonomic dysfunction has been considered to explain these symptoms …

[PDF][PDF] Gastrointestinal manifestations in hereditary transthyretin amyloidosis associated with Glu89Gln mutation

R Nakov, S Sarafov, V Nakov… - J Gastrointestin …, 2019 - researchgate.net
Aims: In the current study we aimed to explore the prevalence of gastrointestinal (GI)
manifestations in hereditary transthyretin amyloid (hATTR) amyloidosis associated with …

Autonomic involvement in hereditary transthyretin amyloidosis (hATTR amyloidosis)

A Gonzalez-Duarte - Clinical Autonomic Research, 2019 - Springer
Purpose Hereditary transthyretin amyloidosis (hATTR amyloidosis) is a progressive disease
primarily characterized by adult-onset sensory, motor, and autonomic neuropathy. In this …

Abnormal small bowel motility in patients with hereditary transthyretin amyloidosis

J Wixner, H Törnblom, P Karling, I Anan… - …, 2018 - Wiley Online Library
Background Gastrointestinal complications are common in hereditary transthyretin amyloid
(ATTR m) amyloidosis. The underlying mechanisms have not been fully elucidated, and the …

Chance or challenge, spoilt for choice? New recommendations on diagnostic and therapeutic considerations in hereditary transthyretin amyloidosis with …

MF Dohrn, M Auer-Grumbach, R Baron, F Birklein… - Journal of …, 2021 - Springer
Hereditary transthyretin amyloidosis is caused by pathogenic variants (ATTR v) in the TTR
gene. Alongside cardiac dysfunction, the disease typically manifests with a severely …