Ruthenium (II) carbon monoxide releasing molecules: Structural perspective, antimicrobial and anti-inflammatory properties

AM Mansour, RM Khaled, E Khaled, SK Ahmed… - Biochemical …, 2022 - Elsevier
Carbon monoxide has recently emerged to promote tissue regeneration, enhance the innate
immune system, and have anti-inflammatory and antibacterial properties. While the first …

Development of triggerable, trackable, and targetable carbon monoxide releasing molecules

LS Lazarus, AD Benninghoff… - Accounts of chemical …, 2020 - ACS Publications
Conspectus Carbon monoxide (CO) is a gaseous signaling molecule produced in humans
via the breakdown of heme in an O2-dependent reaction catalyzed by heme oxygenase …

Water-Soluble carbon monoxide-releasing molecules (CORMs)

H Khan, M Faizan, SUK Niazi, Madiha… - Topics in Current …, 2023 - Springer
Carbon monoxide-releasing molecules (CORMs) are promising candidates for producing
carbon monoxide in the mammalian body for therapeutic purposes. At higher …

Polymer–protein hybrid scaffolds as carriers for CORM-3: platforms for the delivery of carbon monoxide (CO)

D Nguyen, S Oliver, NNM Adnan, C Herbert, C Boyer - RSC advances, 2016 - pubs.rsc.org
Recognised as a signalling molecule in mammals, carbon monoxide (CO) has a number of
beneficial effects, including anti-inflammatory, anti-apoptotic, anti-proliferative and …

Carbon monoxide-releasing micelles for immunotherapy

U Hasegawa, AJ Van Der Vlies, E Simeoni… - Journal of the …, 2010 - ACS Publications
With the discovery of important biological roles of carbon monoxide (CO), the use of this gas
as a therapeutic agent has attracted attention. However, the medical application of this gas …

Ruthenium imidazole oxime carbonyls and their activities as CO-releasing molecules

L Oresmaa, H Tarvainen, K Kolari, M Haukka - Dalton Transactions, 2012 - pubs.rsc.org
Carbon monoxide has been found to possess various beneficial effects in living organisms.
To study the effects of CO further and to develop potential pharmaceutical agents, a …

Emerging concepts on the anti-inflammatory actions of carbon monoxide-releasing molecules (CO-RMs)

R Motterlini, B Haas, R Foresti - Medical Gas Research, 2012 - Springer
Carbon monoxide-releasing molecules (CO-RMs) are a class of organometallo compounds
capable of delivering controlled quantities of CO gas to cells and tissues thus exerting a …

Improving the anti-inflammatory response via gold nanoparticle vectorization of CO-releasing molecules

AR Fernandes, I Mendonça-Martins… - ACS Biomaterials …, 2020 - ACS Publications
CO-releasing molecules (CORMs) have been widely studied for their anti-inflammatory,
antiapoptotic, and antiproliferative effects. CORM-3 is a water-soluble Ru-based metal …

Recent advances on carbon monoxide releasing molecules for antibacterial applications

J Cheng, J Hu - ChemMedChem, 2021 - Wiley Online Library
Carbon monoxide (CO) has been known as an endogenous signaling molecule in addition
to an air pollutant. It plays a critical role in many physiological and pathological processes …

Carbon monoxide-releasing molecules: a pharmacological expedient to counteract inflammation

MJ Alcaraz, MI Guillen, ML Ferrandiz… - Current …, 2008 - ingentaconnect.com
Carbon monoxide (CO) mediates many of the biological effects that are attributed to heme
oxygenase (HO), the enzyme responsible for CO production in mammals. Antioxidant and …