Inflammation and dyslipidemia are critical inducing factors of atherosclerosis. Peroxisome
proliferator-activated receptors (PPARs) are ligand-activated transcription factors and control …

Peroxisome proliferator-activated receptor-α (PPAR-α) belonging to the nuclear hormone
receptor superfamily is a promising target for CVDs which mechanistically improves the …

Atherosclerosis, a chief pathogenic factor of cardiovascular disease, is associated with many
factors including inflammation, dyslipidemia, and oxidative stress. Peroxisome proliferator …

Peroxisome proliferator activated receptors, including PPARα, PPARβ/δ, and PPARγ, are
ligand-activated transcription factors belonging to the nuclear receptor superfamily. They …

Background Atherosclerosis is a chronic and complex disease caused by lipid disorder,
inflammation, and other factors. It is closely related to cardiovascular diseases, the chief …

Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear hormone-
receptor superfamily. Originally cloned in 1990, PPARs were found to be mediators of …

Peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors
that regulate lipid and lipoprotein metabolism, glucose homeostasis and inflammation. The …

The peroxisome proliferator-activated receptors (PPARs) α, β/δ and γ are ligand-activated
transcription factors belonging to the nuclear receptor superfamily. PPARs heterodimerize …

The formation of atherosclerotic plaques is one of the main sources of cardiovascular
disease. In addition to known risk factors such as dyslipidemia, diabetes, obesity, and …

Peroxisome proliferator-activated receptors (PPAR) are implicated in the pathology of
several metabolic diseases including obesity, diabetes, and atherosclerosis. PPAR agonists …