Diagnostic and therapeutic potential of exosomes in cancer: the beginning of a new tale?

H Mirzaei, A Sahebkar, MR Jaafari… - Journal of cellular …, 2017 - Wiley Online Library
Exosomes have emerged as one of the main players in intercellular communication. These
small nano‐sized particles have many roles in various physiological pathways in normal …

A tale of exosomes and their implication in cancer

A Mishra, PS Bharti, N Rani, F Nikolajeff… - Biochimica et Biophysica …, 2023 - Elsevier
Cancer is a cause of high deaths worldwide and also a huge burden for the health system.
Cancer cells have unique properties such as a high rate of proliferation, self-renewal …

Exosome in tumour microenvironment: overview of the crosstalk between normal and cancer cells

C Roma-Rodrigues, AR Fernandes… - BioMed research …, 2014 - Wiley Online Library
Cancer development is a multistep process in which exosomes play important roles.
Exosomes are small vesicles formed in vesicular bodies in the endosomal network. The …

Exosomes: isolation, analysis, and applications in cancer detection and therapy

H Bu, D He, X He, K Wang - Chembiochem, 2019 - Wiley Online Library
Exosomes are cell‐derived small extracellular vesicles that are naturally secreted by all
types of cells and widely distributed in various biofluids. They carry a variety of key bioactive …

Exosomes: The protagonists in the tale of colorectal cancer?

DK Nabariya, R Pallu, VR Yenuganti - Biochimica et Biophysica Acta (BBA) …, 2020 - Elsevier
Exosomes, which facilitate intercellular communication, antigen presentation and shuttling of
biological agents, were initially thought as the cell's garbage cargo but today, after about 40 …

The versatile role of exosomes in cancer progression: diagnostic and therapeutic implications

V Sundararajan, FH Sarkar, TS Ramasamy - Cellular Oncology, 2018 - Springer
Background Recent advances in cancer biology have highlighted the relevance of
exosomes and nanovesicles as carriers of genetic and biological messages between cancer …

Exosomes in cancer disease

M Zöller - Cancer gene profiling: methods and protocols, 2016 - Springer
Cancer diagnosis and therapy is steadily improving. Still, diagnosis is frequently late and
diagnosis and follow-up procedures mostly are time-consuming and expensive. Searching …

The cancer exosomes: Clinical implications, applications and challenges

Z Tang, D Li, S Hou, X Zhu - International journal of cancer, 2020 - Wiley Online Library
The exosome is a small functional vesicle enriched in selected proteins, lipids and nucleic
acids, displaying distinct molecular heterogeneity. Exosomes released can transform the …

Exosomes: diagnostic biomarkers and therapeutic delivery vehicles for cancer

L Jiang, Y Gu, Y Du, J Liu - Molecular pharmaceutics, 2019 - ACS Publications
Exosomes are described as nanoscale extracellular vesicles (EVs) secreted by multiple cell
types and extensively distributed in various biological fluids. They contain multifarious …

[HTML][HTML] Tumorigenesis, diagnosis, and therapeutic potential of exosomes in liver cancer

H Wang, Z Lu, X Zhao - Journal of hematology & oncology, 2019 - Springer
Hepatocellular carcinoma (HCC, also called primary liver cancer) is one of the most fatal
cancers in the world. Due to the insidiousness of the onset of HCC and the lack of effective …