Severe malaria is a global problem, claiming at least 1 million lives annually. Few
adequately powered clinical studies have been directed at improving the management of …

Adjunctive management of malaria : Current Opinion in Infectious Diseases Adjunctive
management of malaria : Current Opinion in Infectious Diseases Log in or Register Subscribe …

Severe malaria kills more than a half million people each year. Based on high-quality
evidence of the efficacy superiority of artesunate over quinine in adults and children with …

This review summarizes progress in treating severe and complicated malaria, which are
global problems, claiming at least one million lives annually, and have been accompanied …

ContextMany US clinicians and laboratory personnel are unfamiliar with the diagnosis and
treatment of malaria. ObjectivesTo examine the evidence base for management of …

In the SEAQUAMAT trial, parenteral artesunate was shown to be associated with a
considerably lower mortality than quinine, and is now the recommended treatment for …

Objective: To review the pharmacodynamics and pharmacotherapeutic use of intravenous
artesunate for the treatment of severe malaria. Data Sources: Literature was retrieved …

The excess of malaria-attributed mortality in the African region is estimated to be well over a
million, mainly because of the premature death of children younger than 5 years of age and …

Severe malaria remains a major cause of mortality and morbidity for children living in many
tropical regions. With the emergence of strains of Plasmodium falciparum resistant to both …

Despite advances in our understanding of malarial pathogenesis much remains unknown.
Antimalarial agents eradicate parasites but no treatments are available to prevent or …