Malaria still claims a heavy toll of deaths and disabilities even at the beginning of the third
millennium. The inappropriate sequential use of drug monotherapy in the past has facilitated …

Drug treatment of severe malaria must be rapidly effective. Suppositories may be valuable
for childhood malaria when circumstances prevent oral or parenteral therapy. We compared …

Documentation on the efficacy of artesunate in Africa is limited, and no experience of
artesunate use in Sudan is documented. Severe malaria in rural areas of Sudan, where …

Background. We compared a conventional empirically derived regimen with a simplified
regimen for parenteral artesunate in severe malaria. Methods. This was a randomized …

In the absence of prompt and efficacious treatment, malaria patients may progress within a
few hours from having minor symptoms to severe disease and death. These last years have …

ACTs are an essential tool in the fight to control and eliminate malaria. They are currently the
most effective drugs against P. falciparum malaria. They should be deployed through …

Malaria remains an important cause of illness and death in children and adults in countries
in which it is endemic. Malaria control requires an integrated approach including prevention …

Over the past two decades, malaria-related deaths have reduced substantially, especially in
African children. However, the global malaria burden still remains high. The recent …

Purpose: The policy for the treatment of severe malaria in Nigeria was revised in June 2011
to parenteral artesunate followed by a full course of artemisinin-based combination therapy …

Background Severe malaria is a medical emergency with high mortality in children below 5
years of age especially in sub-Saharan Africa. Recently, quinine has been replaced by …