Current status in chemotherapy for advanced pancreatic adenocarcinoma

H Cao, D Le, LX Yang - Anticancer research, 2013 - ar.iiarjournals.org
Pancreatic ductal adenocarcinoma (PDA) is one of the most lethal types of cancer in the
United States. Surgical resection remains the only curative treatment, but fewer than 20% of …

[HTML][HTML] Perspectives in the treatment of pancreatic adenocarcinoma

A Cid-Arregui, V Juarez - World journal of gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is an incurable lethal disease whose incidence
rate is growing. There is no effective screening for detection of early stage tumors and, in …

New advances in the treatment of metastatic pancreatic cancer

M Schober, MA Javed, G Beyer, N Le, A Vinci, M Sund… - Digestion, 2015 - karger.com
Background: Pancreatic ductal adenocarcinoma (PDAC) is characterised by an extremely
poor overall survival (OS) compared to other solid tumours. As the incidence of the disease …

[HTML][HTML] State of the art biological therapies in pancreatic cancer

M Di Marco, E Grassi, S Durante… - World Journal of …, 2016 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies with a five-
year survival rate of approximately 5%. Several target agents have been tested in PDAC, but …

Treatment of advanced pancreatic cancer: from gemcitabine single agent to combinations and targeted therapy

F Rivera, S López-Tarruella, ME Vega-Villegas… - Cancer Treatment …, 2009 - Elsevier
The prognosis of advanced pancreatic adenocarcinoma is still poor nowadays. Gemcitabine
in monotherapy (30-min infusion) has been the standard of treatment during the last decade …

Advanced or metastatic pancreatic cancer: molecular targeted therapies

S Bayraktar, CM Rocha‐Lima - Mount Sinai Journal of Medicine …, 2010 - Wiley Online Library
Patients with pancreatic cancer normally present with advanced disease that is lethal and
notoriously difficult to treat. However, clinical developments over the past decade have been …

State of the art and future directions of pancreatic ductal adenocarcinoma therapy

C Neuzillet, A Tijeras-Raballand, P Bourget… - Pharmacology & …, 2015 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is expected to become the second cause of
cancer-related death in 2030. PDAC is the poorest prognostic tumor of the digestive tract …

[HTML][HTML] Advanced pancreatic cancer: a meta-analysis of clinical trials over thirty years

BR Hall, A Cannon, P Atri, CS Wichman, LM Smith… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Background In contrast to other cancers, survival rates for pancreatic ductal
adenocarcinoma (PDAC) patients have improved but minimally over the past thirty years …

Pancreatic cancer: from state-of-the-art treatments to promising novel therapies

I Garrido-Laguna, M Hidalgo - Nature reviews Clinical oncology, 2015 - nature.com
Pancreatic cancer is expected to be the second deadliest malignancy in the USA by 2020.
The survival rates for patients with other gastrointestinal malignancies have increased …

From state-of-the-art treatments to novel therapies for advanced-stage pancreatic cancer

C Nevala-Plagemann, M Hidalgo… - Nature reviews Clinical …, 2020 - nature.com
Improvements in the outcomes of patients with pancreatic ductal adenocarcinoma (PDAC)
have lagged behind advances made in the treatment of many other malignancies over the …