Increasing evidence suggests that crosstalk between airway epithelial cells (AEC) and
adjacent dendritic cells (DC) tightly regulates airway mucosal DC function in steady state …

Dendritic cells (DCs) appear to be strategically implicated in allergic diseases, including
asthma. Matrix metalloproteinase (MMP)-9 mediates transmigration of inflammatory …

Hallmarks of chronic obstructive pulmonary disease (COPD) include innate inflammation
and remodeling of small airways, which begin in early disease, and the development of lung …

Introduction Allergic asthma has been mainly attributed to T helper type 2 (Th2) and
proinflammatory responses but many cellular processes remain elusive. There is increasing …

Ambient particulate matter, including diesel exhaust particles (DEP), promotes the
development of allergic disorders. DEP increase oxidative stress and influence human …

Plasmacytoid dendritic cells (PDCs) are critical for defense against respiratory viruses
because of their propensity to secrete high levels of type I interferons (IFN). The functions of …

Background Allergic asthma is a prevalent inflammatory disease of the airways caused by
dysregulated immune balance in the lungs with incompletely understood pathogenesis. The …

Exposure to urban particulate matter (UPM) exacerbates asthmatic lung inflammation. Lung
dendritic cells (DCs) are critical for stimulating T cell immunity and in maintaining airway …

Asthma is an allergic chronic respiratory disease that affects more than 300 million people
around the world. Dysbiosis of intestinal commensal microbiota influences the development …

APCs, including dendritic cells (DC), are central to Ag surveillance in the respiratory tract
(RT). Research in this area is dominated by mouse studies on purportedly representative RT …